Basis: Trailing twelve months (TTM net income over TTM revenue). Source: stored company filings and market data; unavailable inputs remain N/A.
Is the net profit margin high or low?
The net profit margin of -435.21% is 427% below its 5-year average of -82.54%, near the high end of its 5-year range (-3998.49%–49.55%).
62.95% above its 12-month average of -1174.65%.
Reported quarterly profit margin; no daily interpolation. Q2 FY2026 (2026-06-30): -1457.40%.
NET PROFIT MARGIN
-435.21%
NET PROFIT MARGIN AVG TTM
-1174.65%
NET PROFIT MARGIN AVG 3Y
-26.10%
NET PROFIT MARGIN AVG 5Y
-82.54%
NET PROFIT MARGIN AVG 10Y
-130.07%
NET PROFIT MARGIN AVG 15Y
N/A
NET PROFIT MARGIN AVG 20Y
N/A
CURRENT VS TTM AVG
+62.95%
CURRENT VS 3Y AVG
-1567.52%
CURRENT VS 5Y AVG
-427.26%
CURRENT VS 10Y AVG
-234.59%
CURRENT VS 15Y AVG
N/A
CURRENT VS 20Y AVG
N/A
SECTOR MEDIAN · HEALTHCARE
-0.35%
median of 862 covered companies
CURRENT VS SECTOR MEDIAN
-124245.71%
vs the sector median at left
CytomX Therapeutics, Inc.
Market Cap
$557.32M
Net Profit Margin
-435.21%
TTM Avg
-1174.65%
3Y Avg
-26.10%
5Y Avg
-82.54%
Market Cap
$548.51M
Net Profit Margin
-41.34%
TTM Avg
-365.72%
3Y Avg
-7572.59%
5Y Avg
-5048.40%
Market Cap
$571.13M
Net Profit Margin
40.49%
TTM Avg
5.54%
3Y Avg
-11349.71%
5Y Avg
-11563.54%
Market Cap
$538.01M
Net Profit Margin
-10599.76%
TTM Avg
-44116.54%
3Y Avg
-22058.27%
5Y Avg
-14705.51%
Market Cap
$578.40M
Net Profit Margin
-144.63%
TTM Avg
-132.38%
3Y Avg
-98.61%
5Y Avg
-109.15%
Market Cap
$533.04M
Net Profit Margin
0.00%
TTM Avg
0.00%
3Y Avg
0.00%
5Y Avg
0.00%
Market Cap
$531.98M
Net Profit Margin
0.56%
TTM Avg
-33.88%
3Y Avg
-929.83%
5Y Avg
-984.73%
Market Cap
$531.52M
Net Profit Margin
0.00%
TTM Avg
0.00%
3Y Avg
0.00%
5Y Avg
0.00%
| NAME | MARKET CAP | NET PROFIT MARGIN | TTM | 3Y | 5Y |
|---|---|---|---|---|---|
| CytomX Therapeutics, Inc. (CTMX) | $557.32M | -435.21% | -1174.65% | -26.10% | -82.54% |
| MiniMed Group, Inc. (MMEDV)vs › | $560.00M | N/A | N/A | N/A | N/A |
| Phathom Pharmaceuticals, Inc. (PHAT)vs › | $548.51M | -41.34% | -365.72% | -7572.59% | -5048.40% |
| CorMedix Inc. (CRMD)vs › | $571.13M | 40.49% | 5.54% | -11349.71% | -11563.54% |
| ProKidney Corp. (PROK)vs › | $538.01M | -10599.76% | -44116.54% | -22058.27% | -14705.51% |
| Aquestive Therapeutics, Inc. (AQST)vs › | $578.40M | -144.63% | -132.38% | -98.61% | -109.15% |
| Monopar Therapeutics Inc. (MNPR)vs › | $533.04M | 0.00% | 0.00% | 0.00% | 0.00% |
| Delcath Systems, Inc. (DCTH)vs › | $531.98M | 0.56% | -33.88% | -929.83% | -984.73% |
| Nuvectis Pharma, Inc. (NVCT)vs › | $531.52M | 0.00% | 0.00% | 0.00% | 0.00% |
| OrthoPediatrics Corp. (KIDS)vs › | $583.31M | -15.72% | -17.63% | -12.08% | -18.54% |
Operating Margin
-29.4%
Net Profit Margin
-435.2%
Net Profit Margin = Net Income / Revenue
Net profit margin is the percentage of revenue that becomes net income after all expenses, taxes, and interest.
Expanded definitions: Investopedia, Wikipedia, Corporate Finance Institute
| DATE | NET PROFIT MARGIN |
|---|---|
| 2026-06-30 | -1457.40% |
| 2026-03-31 | -177.89% |
| 2025-12-31 | -3998.49% |
| 2025-09-30 | -238.62% |
| 2025-06-30 | -0.83% |
| 2025-03-31 | 46.20% |
| 2024-12-31 | 49.55% |
| 2024-09-30 | 17.16% |
| 2024-06-30 | -26.02% |
| 2024-03-31 | 33.26% |
| 2023-12-31 | 3.15% |
| 2023-09-30 | 11.34% |
| 2023-06-30 | -4.40% |
| 2023-03-31 | -14.09% |
| 2022-12-31 | -43.61% |
| 2022-09-30 | -260.73% |
| 2022-06-30 | -229.49% |
| 2022-03-31 | -353.77% |
| 2021-12-31 | -132.95% |
| 2021-09-30 | -128.41% |
| 2021-06-30 | -118.14% |
| 2021-03-31 | -97.39% |
| 2020-12-31 | -89.79% |
| 2020-09-30 | -82.70% |
| 2020-06-30 | -94.41% |
| 2020-03-31 | 24.61% |
| 2019-12-31 | -428.26% |
| 2019-09-30 | -221.24% |
| 2019-06-30 | -321.31% |
| 2019-03-31 | -47.90% |
| 2018-12-31 | -281.00% |
| 2018-09-30 | -187.31% |
| 2018-06-30 | -63.02% |
| 2018-03-31 | -109.23% |
| 2017-12-31 | 2.29% |
| 2017-09-30 | -42.44% |
| 2017-06-30 | -288.12% |
| 2017-03-31 | -70.86% |
| 2016-12-31 | -223.74% |
| 2016-09-30 | -424.49% |
| 2016-06-30 | -458.18% |
| 2016-03-31 | -721.05% |
| 2015-12-31 | -577.82% |
| 2015-09-30 | -612.17% |
| 2015-06-30 | -284.19% |
| 2015-03-31 | -356.54% |
| 2014-12-31 | -257.23% |
| 2014-09-30 | -187.42% |
| 2014-06-30 | -912.91% |
| 2014-03-31 | -2843.31% |
