Arcturus Therapeutics Holdings (ARCT) Operating Margin: History & Chart

Arcturus Therapeutics Holdings Inc.(ARCT)

Biotechnology · San Diego, CA

$14.66+1.63 (+12.51%)

Delayed quote: Oct 5, 2026, 4:00 PM EDT

About Arcturus Therapeutics Holdings Inc.

Arcturus Therapeutics Holdings Inc. is a biotechnology company focused on RNA-based medicines, developing a pipeline of vaccines for infectious diseases alongside treatments for rare liver and respiratory conditions across the United States. Its notable development programs encompass LUNAR-OTC, designed for ornithine transcarbamylase (OTC) deficiency, and LUNAR-CF, targeting cystic fibrosis lung disease caused by specific CFTR gene mutations. The company also advances vaccine initiatives such as LUNAR-COV19 and LUNAR-FLU. Arcturus has cultivated a range of strategic collaborations, including partnerships with Vinbiocare Biotechnology Joint Stock Company for manufacturing COVID-19 vaccines; Janssen Pharmaceuticals, Inc., to create nucleic acid-based therapies for hepatitis B virus; Ultragenyx Pharmaceutical, Inc., for developing mRNA therapeutics aimed at rare disease targets; CureVac AG, to progress mRNA therapeutic and vaccine candidates across various indications; the Singapore Economic Development Board and Duke-NUS Medical School, specifically for the LUNAR-COV19 vaccine; and Millennium Pharmaceuticals, Inc., focused on discovering siRNA medicines for non-alcoholic steatohepatitis (NASH). Founded in 2013, Arcturus Therapeutics maintains its corporate headquarters in San Diego, California.

San Diego, CA

109 employees

arcturusrx.com

Healthcare / Biotechnology

Sector: Healthcare
Industry: Biotechnology
CEO: Joseph E. Payne

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ARCT Operating Margin Metrics

OPERATING MARGIN

-111.51%

OPERATING MARGIN AVG TTM

-1381.01%

OPERATING MARGIN AVG 3Y

-254.17%

OPERATING MARGIN AVG 5Y

-273.51%

OPERATING MARGIN AVG 10Y

-235.71%

OPERATING MARGIN AVG 15Y

-114.52%

OPERATING MARGIN AVG 20Y

N/A

CURRENT VS TTM AVG

+91.93%

CURRENT VS 3Y AVG

+56.13%

CURRENT VS 5Y AVG

+59.23%

CURRENT VS 10Y AVG

+52.69%

CURRENT VS 15Y AVG

+2.63%

CURRENT VS 20Y AVG

N/A

SECTOR MEDIAN · HEALTHCARE

0.00%

median of 496 covered companies

CURRENT VS SECTOR MEDIAN

N/A

vs the sector median at left

NAME	MARKET CAP	OPERATING MARGIN	TTM	3Y	5Y
Arcturus Therapeutics Holdings Inc. (ARCT)	$416.68M	-111.51%	-1381.01%	-254.17%	-273.51%
Carlsmed, Inc. (CARL)vs ›	$415.93M	-61.09%	-74.66%	-94.75%	-94.75%
Atea Pharmaceuticals, Inc. (AVIR)vs ›	$410.54M	0.00%	0.00%	0.00%	2.78%
Eikon Therapeutics, Inc. Common Stock (EIKN)vs ›	$408.21M	0.00%	0.00%	0.00%	0.00%
Shoulder Innovations, Inc. (SI)vs ›	$406.47M	-58.53%	-50.96%	-52.76%	-52.76%
Editas Medicine, Inc. (EDIT)vs ›	$428.16M	-245.15%	-511.19%	-596.30%	-548.32%
Capricor Therapeutics, Inc. (CAPR)vs ›	$447.43M	0.00%	-95.56%	-362.67%	-2402.18%
Kyverna Therapeutics, Inc. (KYTX)vs ›	$384.23M	0.00%	0.00%	-104.57%	-176.82%
Assembly Biosciences, Inc. (ASMB)vs ›	$450.64M	-11.75%	-88.01%	-269.63%	-547.01%
DiaMedica Therapeutics Inc. (DMAC)vs ›	$453.70M	0.00%	0.00%	0.00%	0.00%

NAME

MARKET CAP

OPERATING MARGIN

TTM

Arcturus Therapeutics Holdings Inc. (ARCT)

$416.68M

-111.51%

-1381.01%

-254.17%

-273.51%

Carlsmed, Inc. (CARL)vs ›

$415.93M

-61.09%

-74.66%

-94.75%

Atea Pharmaceuticals, Inc. (AVIR)vs ›

$410.54M

0.00%

2.78%

Eikon Therapeutics, Inc. Common Stock (EIKN)vs ›

$408.21M

0.00%

Shoulder Innovations, Inc. (SI)vs ›

$406.47M

-58.53%

-50.96%

-52.76%

Editas Medicine, Inc. (EDIT)vs ›

$428.16M

-245.15%

-511.19%

-596.30%

-548.32%

Capricor Therapeutics, Inc. (CAPR)vs ›

$447.43M

0.00%

-95.56%

-362.67%

-2402.18%

Kyverna Therapeutics, Inc. (KYTX)vs ›

$384.23M

0.00%

-104.57%

-176.82%

Assembly Biosciences, Inc. (ASMB)vs ›

$450.64M

-11.75%

-88.01%

-269.63%

-547.01%

DiaMedica Therapeutics Inc. (DMAC)vs ›

$453.70M

0.00%

Operating Margin FAQ

What is the operating margin for Arcturus Therapeutics Holdings Inc. (ARCT)?

The operating margin for ARCT stock is -111.51%.

Is Arcturus Therapeutics Holdings Inc.'s operating margin high or low?

The operating margin of -111.51% is 59% above its 5-year average of -273.51%, near the high end of its 5-year range (-4881.97%–75.77%).

What is the TTM average operating margin for Arcturus Therapeutics Holdings Inc. (ARCT)?

The TTM average operating margin for ARCT stock is -1381.01%.

What is the 3Y average operating margin for Arcturus Therapeutics Holdings Inc. (ARCT)?

The 3Y average operating margin for ARCT stock is -254.17%.

What is the 5Y average operating margin for Arcturus Therapeutics Holdings Inc. (ARCT)?

The 5Y average operating margin for ARCT stock is -273.51%.

What is the 10Y average operating margin for Arcturus Therapeutics Holdings Inc. (ARCT)?

The 10Y average operating margin for ARCT stock is -235.71%.

What is the 15Y average operating margin for Arcturus Therapeutics Holdings Inc. (ARCT)?

The 15Y average operating margin for ARCT stock is -114.52%.

DATE	OPERATING MARGIN
2026-06-30	-863.30%
2026-03-31	-4881.97%
2025-12-31	-1016.13%
2025-09-30	-96.27%
2025-06-30	-47.39%
2025-03-31	-57.27%
2024-12-31	-159.02%
2024-09-30	-27.66%
2024-06-30	-45.95%
2024-03-31	-93.29%
2023-12-31	-72.86%
2023-09-30	-44.53%
2023-06-30	-526.42%
2023-03-31	18.38%
2022-12-31	75.77%
2022-09-30	-275.32%
2022-06-30	-81.53%
2022-03-31	-960.70%
2021-12-31	-649.72%
2021-09-30	-2208.49%
2021-06-30	-2684.66%
2021-03-31	-2711.14%
2020-12-31	-1388.83%
2020-09-30	-897.47%
2020-06-30	-432.47%
2020-03-31	-357.60%
2019-12-31	-364.45%
2019-09-30	-229.54%
2019-06-30	-5.63%
2019-03-31	-149.61%
2018-12-31	-9.38%
2018-09-30	-127.26%
2018-06-30	-422.13%
2018-03-31	-281.88%
2017-12-31	-1.11%
2017-09-30	-87.74%
2017-06-30	-101.65%
2017-03-31	-94.58%
2016-12-31	0.00%
2016-09-30	0.00%
2016-06-30	0.00%
2016-03-31	0.00%
2015-12-31	0.00%
2015-09-30	0.00%
2015-06-30	0.00%
2015-03-31	0.00%
2014-12-31	0.00%
2014-09-30	0.00%
2014-06-30	0.00%
2014-03-31	0.00%
2013-12-31	0.00%
2013-09-30	0.00%
2013-06-30	0.00%
2013-03-31	0.00%
2012-12-31	0.00%
2012-09-30	0.00%
2012-06-30	0.00%

DATE

OPERATING MARGIN

2026-06-30

-863.30%

2026-03-31

-4881.97%

2025-12-31

-1016.13%

2025-09-30

-96.27%

2025-06-30

-47.39%

2025-03-31

-57.27%

2024-12-31

-159.02%

2024-09-30

-27.66%

2024-06-30

-45.95%

2024-03-31

-93.29%

2023-12-31

-72.86%

2023-09-30

-44.53%

2023-06-30

-526.42%

2023-03-31

18.38%

2022-12-31

75.77%

2022-09-30

-275.32%

2022-06-30

-81.53%

2022-03-31

-960.70%

2021-12-31

-649.72%

2021-09-30

-2208.49%

2021-06-30

-2684.66%

2021-03-31

-2711.14%

2020-12-31

-1388.83%

2020-09-30

-897.47%

2020-06-30

-432.47%

2020-03-31

-357.60%

2019-12-31

-364.45%

2019-09-30

-229.54%

2019-06-30

-5.63%

2019-03-31

-149.61%

2018-12-31

-9.38%

2018-09-30

-127.26%

2018-06-30

-422.13%

2018-03-31

-281.88%

2017-12-31

-1.11%

2017-09-30

-87.74%

2017-06-30

-101.65%

2017-03-31

-94.58%

2016-12-31

0.00%

2016-09-30

0.00%

2016-06-30

0.00%

2016-03-31

0.00%

2015-12-31

0.00%

2015-09-30

0.00%

2015-06-30

0.00%

2015-03-31

0.00%

2014-12-31

0.00%

2014-09-30

0.00%

2014-06-30

0.00%

2014-03-31

0.00%

2013-12-31

0.00%

2013-09-30

0.00%

2013-06-30

0.00%

2013-03-31

0.00%

2012-12-31

0.00%

2012-09-30

0.00%

2012-06-30

0.00%

Operating Margin: -111.51%

ARCT Operating Margin

ARCT Average Operating Margin Chart

ARCT Current vs Average Operating Margin Chart

ARCT Operating Margin Metrics

ARCT Competitors' Operating Margin

Operating Efficiency

Operating Margin Formula & Definition

Operating Margin FAQ

ARCT Operating Margin History

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