TriSalus Life Sciences, Inc. (TLSI) vs Vanda Pharmaceuticals Inc. (VNDA)
A side-by-side comparison of TriSalus Life Sciences, Inc. and Vanda Pharmaceuticals Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.
TLSI
TriSalus Life Sciences, Inc.
$4.39HealthcareDelayed quote: Oct 6, 2026, 3:04 PM EDT
VNDA
Vanda Pharmaceuticals Inc.
$4.49HealthcareDelayed quote: Oct 6, 2026, 3:05 PM EDT
Total return — TLSI vs VNDA
growth of $100 · dividends reinvested · last 6yTLSI -58.4% (-13.6%/yr)VNDA -68.7% (-17.6%/yr)TLSI compounded faster over this window
TLSI VNDA
TLSI vs VNDA: by the numbers
- •TLSI is the larger company ($270M vs $270M market cap).
- •Both run net losses; TLSI's is the smaller (-62.59% vs -127.41% net margin).
Metrics side by side
Valuation
| Metric | TLSI | VNDA |
|---|---|---|
| P/S ratio | 6.00 | 1.25 |
| P/B ratio | 41.27 | 1.23 |
Profitability
| Metric | TLSI | VNDA |
|---|---|---|
| Gross margin | 85.79% | 92.82% |
| Operating margin | -59.68% | -69.95% |
| Net margin | -62.59% | -127.41% |
| ROE | -430.72% | -124.83% |
| ROIC | -59.50% | -74.73% |
Growth (annualized)
| Metric | TLSI | VNDA |
|---|---|---|
| Revenue CAGR (5Y) | N/A | -3.56% |
| Total return CAGR (5Y) | -15.05% | -23.91% |
Frequently asked
- How have TLSI and VNDA total returns compared?
- Over the past 5 years, TLSI delivered -15.05% and VNDA delivered -23.91% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.