Which has the lower trailing P/E, SYM or TMDX?

TMDX has the lower trailing P/E: SYM trades at 454.97 and TMDX at 21.29. P/E is one valuation measure and does not by itself establish which business is cheaper.

Which has grown faster, SYM or TMDX?

Over the past five years, SYM grew revenue faster — SYM at a 89.66% CAGR versus TMDX at 86.12%.

Is SYM or TMDX more profitable?

TMDX runs the higher net margin — SYM at 0.48% versus TMDX at 22.69%.

How have SYM and TMDX total returns compared?

Over the past 5 years, SYM delivered 33.10% and TMDX delivered 21.90% annualized total return. Past performance doesn't predict future results.

Symbotic Inc. (SYM) vs TransMedics Group, Inc. (TMDX)

A side-by-side comparison of Symbotic Inc. and TransMedics Group, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of September 10, 2026. Differences are shown without an overall score or investment verdict.

Different business models: SYM is classified in Industrials; TMDX is classified in Healthcare. Margin, capital intensity, and valuation differences should be interpreted in that sector context.

SYM

Symbotic Inc.

$27.03B

$42.13IndustrialsDelayed quote: Sep 11, 2026, 4:00 PM EDT

TMDX

TransMedics Group, Inc.

$2.84B

$82.18HealthcareDelayed quote: Sep 11, 2026, 4:00 PM EDT

Total return — SYM vs TMDX

growth of $100 · dividends reinvested · last 6y

SYM +315.8% (+26.8%/yr)TMDX +153.0% (+16.7%/yr)SYM compounded faster over this window

SYM TMDX

SYM vs TMDX: by the numbers

•SYM is the larger company ($27.03B vs $2.84B market cap).
•TMDX trades at the lower trailing earnings multiple (21.29 vs 454.97 P/E), one valuation lens rather than an overall verdict.
•TMDX converts more revenue to profit (22.69% vs 0.48% net margin).
•SYM grew revenue faster over the past five years (89.66% vs 86.12% CAGR).

Metrics side by side

Valuation

Metric	SYM	TMDX
P/E ratio	454.97	21.29
Forward P/E	201.99	55.39
P/S ratio	10.22	4.25
P/B ratio	38.14	5.48
EV / EBITDA	327.78	27.41
FCF yield	2.73%	2.78%

Profitability

Metric	SYM	TMDX
Gross margin	21.60%	58.69%
Operating margin	1.25%	12.21%
Net margin	0.48%	22.69%
ROE	1.78%	29.28%
ROIC	2.39%	5.87%

Growth (annualized)

Metric	SYM	TMDX
Revenue CAGR (5Y)	89.66%	86.12%
FCF CAGR (5Y)	98.71%	N/A
Total return CAGR (5Y)	33.10%	21.90%

Frequently asked

Which has the lower trailing P/E, SYM or TMDX?: TMDX has the lower trailing P/E: SYM trades at 454.97 and TMDX at 21.29. P/E is one valuation measure and does not by itself establish which business is cheaper.
Which has grown faster, SYM or TMDX?: Over the past five years, SYM grew revenue faster — SYM at a 89.66% CAGR versus TMDX at 86.12%.
Is SYM or TMDX more profitable?: TMDX runs the higher net margin — SYM at 0.48% versus TMDX at 22.69%.
How have SYM and TMDX total returns compared?: Over the past 5 years, SYM delivered 33.10% and TMDX delivered 21.90% annualized total return. Past performance doesn't predict future results.

Go deeper

Full SYM analysis Full TMDX analysis Interactive comparison tool

Dig into the metrics

Symbotic P/E ratio TransMedics P/E ratio Symbotic ROE TransMedics ROE Symbotic operating margin TransMedics operating margin Symbotic revenue growth TransMedics revenue growth Symbotic free cash flow TransMedics free cash flow

Symbotic & TransMedics appear in these rankings

Fastest Revenue Growth Stocks Highest ROE Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified September 10, 2026.