Sarepta Therapeutics, Inc. (SRPT) vs Xencor, Inc. (XNCR)
A side-by-side comparison of Sarepta Therapeutics, Inc. and Xencor, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.
SRPT
Sarepta Therapeutics, Inc.
$17.31HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT
XNCR
Xencor, Inc.
$24.36HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT
Total return — SRPT vs XNCR
growth of $100 · dividends reinvested · last 10ySRPT -71.5% (-11.8%/yr)XNCR +10.1% (+1.0%/yr)XNCR compounded faster over this window
SRPT XNCR
SRPT vs XNCR: by the numbers
- •SRPT is the larger company ($1.83B vs $1.81B market cap).
- •Both run net losses; SRPT's is the smaller (-6.93% vs -155.59% net margin).
- •SRPT grew revenue faster over the past five years (26.90% vs 0.47% CAGR).
Metrics side by side
Valuation
| Metric | SRPT | XNCR |
|---|---|---|
| Forward P/E | 5.38 | N/A |
| P/S ratio | 0.93 | 17.21 |
| P/B ratio | 1.20 | 3.59 |
Profitability
| Metric | SRPT | XNCR |
|---|---|---|
| Gross margin | 58.56% | 91.63% |
| Operating margin | -29.92% | -141.35% |
| Net margin | -6.93% | -155.59% |
| ROE | -8.95% | -32.46% |
| ROIC | -5.33% | -33.60% |
Growth (annualized)
| Metric | SRPT | XNCR |
|---|---|---|
| Revenue CAGR (5Y) | 26.90% | 0.47% |
| Total return CAGR (5Y) | -28.74% | -6.46% |
Frequently asked
- Which has grown faster, SRPT or XNCR?
- Over the past five years, SRPT grew revenue faster — SRPT at a 26.90% CAGR versus XNCR at 0.47%.
- How have SRPT and XNCR total returns compared?
- Over the past 10 years, SRPT delivered -11.94% and XNCR delivered 0.77% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
Sarepta Therapeutics ROEXencor ROESarepta Therapeutics operating marginXencor operating marginSarepta Therapeutics revenue growthXencor revenue growthSarepta Therapeutics free cash flowXencor free cash flow
Sarepta Therapeutics & Xencor appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.