Which has the lower trailing P/E, SNY or SYK?

SYK has the lower trailing P/E: SNY trades at 80.55 and SYK at 33.38. P/E is one valuation measure and does not by itself establish which business is cheaper.

Which has grown faster, SNY or SYK?

Over the past five years, SYK grew revenue faster — SNY at a 4.96% CAGR versus SYK at 9.72%.

Does SNY or SYK pay a bigger dividend?

SNY yields 5.39% and SYK yields 1.08% based on trailing dividends and the latest price.

Is SNY or SYK more profitable?

SYK runs the higher net margin — SNY at 8.10% versus SYK at 14.43%.

How have SNY and SYK total returns compared?

Over the past 10 years, SNY delivered 5.69% and SYK delivered 12.13% annualized total return. Past performance doesn't predict future results.

Sanofi (SNY) vs Stryker Corporation (SYK)

A side-by-side comparison of Sanofi and Stryker Corporation across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of August 28, 2026. Differences are shown without an overall score or investment verdict.

SNY

Sanofi

$107.40B

$44.73HealthcareDelayed quote: Aug 28, 2026, 12:20 PM EDT

SYK

Stryker Corporation

$125.43B

$327.19HealthcareDelayed quote: Aug 28, 2026, 12:25 PM EDT

Total return — SNY vs SYK

growth of $100 · dividends reinvested · last 10y

SNY +72.2% (+5.6%/yr)SYK +219.3% (+12.3%/yr)SYK compounded faster over this window

SNY SYK

SNY vs SYK: by the numbers

•SYK is the larger company ($125.43B vs $107.40B market cap).
•SYK trades at the lower trailing earnings multiple (33.38 vs 80.55 P/E), one valuation lens rather than an overall verdict.
•SYK converts more revenue to profit (14.43% vs 8.10% net margin).
•SYK grew revenue faster over the past five years (9.72% vs 4.96% CAGR).
•SNY pays the higher dividend yield (5.39% vs 1.08%).

Metrics side by side

Valuation

Metric	SNY	SYK
P/E ratio	80.55	33.38
Forward P/E	N/A	21.44
P/S ratio	1.89	4.81
P/B ratio	1.36	5.18
EV / EBITDA	10.17	19.59
FCF yield	12.72%	3.78%

Profitability

Metric	SNY	SYK
Gross margin	73.01%	65.17%
Operating margin	14.74%	22.03%
Net margin	8.10%	14.43%
ROE	5.82%	15.55%
ROIC	5.42%	9.82%

Dividends

Metric	SNY	SYK
Dividend yield	5.39%	1.08%
Payout ratio	64.36%	40.99%

Growth (annualized)

Metric	SNY	SYK
Revenue CAGR (5Y)	4.96%	9.72%
EPS CAGR (5Y)	-8.92%	14.79%
FCF CAGR (5Y)	12.83%	9.60%
Total return CAGR (5Y)	1.38%	4.41%

Frequently asked

Which has the lower trailing P/E, SNY or SYK?: SYK has the lower trailing P/E: SNY trades at 80.55 and SYK at 33.38. P/E is one valuation measure and does not by itself establish which business is cheaper.
Which has grown faster, SNY or SYK?: Over the past five years, SYK grew revenue faster — SNY at a 4.96% CAGR versus SYK at 9.72%.
Does SNY or SYK pay a bigger dividend?: SNY yields 5.39% and SYK yields 1.08% based on trailing dividends and the latest price.
Is SNY or SYK more profitable?: SYK runs the higher net margin — SNY at 8.10% versus SYK at 14.43%.
How have SNY and SYK total returns compared?: Over the past 10 years, SNY delivered 5.69% and SYK delivered 12.13% annualized total return. Past performance doesn't predict future results.

Go deeper

Full SNY analysis Full SYK analysis Interactive comparison tool

Dig into the metrics

Sanofi P/E ratio Stryker P/E ratio Sanofi dividend yield Stryker dividend yield Sanofi ROE Stryker ROE Sanofi operating margin Stryker operating margin Sanofi revenue growth Stryker revenue growth Sanofi free cash flow Stryker free cash flow

Sanofi & Stryker appear in these rankings

Highest Dividend Yield Stocks Highest FCF Yield Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified August 28, 2026.