Shoulder Innovations, Inc. (SI) vs TransMedics Group, Inc. (TMDX)
A side-by-side comparison of Shoulder Innovations, Inc. and TransMedics Group, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of August 5, 2026. Differences are shown without an overall score or investment verdict.
SI
Shoulder Innovations, Inc.
$22.26HealthcareDelayed quote: Aug 5, 2026, 3:33 PM EDT
TMDX
TransMedics Group, Inc.
$76.21HealthcareDelayed quote: Aug 5, 2026, 3:35 PM EDT
Total return — SI vs TMDX
growth of $100 · dividends reinvested · last 1ySI +50.8%TMDX -32.1%SI compounded faster
SI TMDX
SI vs TMDX: by the numbers
- •TMDX is the larger company ($2.63B vs $462M market cap).
- •TMDX is profitable (22.69% net margin) while SI runs a net loss (-81.78%).
Metrics side by side
Valuation
| Metric | SI | TMDX |
|---|---|---|
| P/E ratio | N/A | 20.92 |
| Forward P/E | N/A | 44.14 |
| P/S ratio | 8.70 | 4.92 |
| P/B ratio | 3.52 | 6.35 |
| PEG ratio | N/A | 0.05 |
| EV / EBITDA | N/A | 30.86 |
| FCF yield | N/A | 2.40% |
Profitability
| Metric | SI | TMDX |
|---|---|---|
| Gross margin | 75.48% | 58.69% |
| Operating margin | -57.48% | 12.21% |
| Net margin | -81.78% | 22.69% |
| ROE | -33.14% | 29.28% |
| ROIC | -14.80% | 10.94% |
Growth (annualized)
| Metric | SI | TMDX |
|---|---|---|
| Revenue CAGR (5Y) | N/A | 86.12% |
| Total return CAGR (5Y) | N/A | 23.71% |
Frequently asked
- Is SI or TMDX more profitable?
- TMDX runs the higher net margin — SI at -81.78% versus TMDX at 22.69%.
Go deeper
Dig into the metrics
Shoulder Innovations P/E ratioTransMedics P/E ratioShoulder Innovations dividend yieldTransMedics dividend yieldShoulder Innovations ROETransMedics ROEShoulder Innovations operating marginTransMedics operating marginShoulder Innovations revenue growthTransMedics revenue growthShoulder Innovations free cash flowTransMedics free cash flow
Shoulder Innovations & TransMedics appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified August 5, 2026.