Shoulder Innovations, Inc. (SI) vs TransMedics Group, Inc. (TMDX)
A side-by-side comparison of Shoulder Innovations, Inc. and TransMedics Group, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of September 13, 2026. Differences are shown without an overall score or investment verdict.
SI
Shoulder Innovations, Inc.
$18.16HealthcareDelayed quote: Sep 18, 2026, 4:00 PM EDT
TMDX
TransMedics Group, Inc.
$86.42HealthcareDelayed quote: Sep 18, 2026, 4:00 PM EDT
Total return — SI vs TMDX
growth of $100 · dividends reinvested · last 1ySI +23.1% (+23.1%/yr)TMDX -30.9% (-30.9%/yr)SI compounded faster over this window
SI TMDX
SI vs TMDX: by the numbers
- •TMDX is the larger company ($2.99B vs $377M market cap).
- •TMDX is profitable (22.69% net margin) while SI runs a net loss (-58.33%).
Metrics side by side
Valuation
| Metric | SI | TMDX |
|---|---|---|
| P/E ratio | N/A | 22.39 |
| Forward P/E | N/A | 58.26 |
| P/S ratio | 6.27 | 4.47 |
| P/B ratio | 3.03 | 5.77 |
| EV / EBITDA | N/A | 28.65 |
| FCF yield | N/A | 2.65% |
Profitability
| Metric | SI | TMDX |
|---|---|---|
| Gross margin | 77.34% | 58.69% |
| Operating margin | -58.53% | 12.21% |
| Net margin | -58.33% | 22.69% |
| ROE | -28.18% | 29.28% |
| ROIC | -25.26% | 5.87% |
Growth (annualized)
| Metric | SI | TMDX |
|---|---|---|
| Revenue CAGR (5Y) | N/A | 86.12% |
| Total return CAGR (5Y) | N/A | 20.95% |
Frequently asked
- Is SI or TMDX more profitable?
- TMDX runs the higher net margin — SI at -58.33% versus TMDX at 22.69%.
Go deeper
Dig into the metrics
TransMedics P/E ratioShoulder Innovations ROETransMedics ROEShoulder Innovations operating marginTransMedics operating marginShoulder Innovations revenue growthTransMedics revenue growthShoulder Innovations free cash flowTransMedics free cash flow
Shoulder Innovations & TransMedics appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified September 13, 2026.