Shoulder Innovations, Inc. (SI) vs TransMedics Group, Inc. (TMDX)

TMDX leads on 5 of 7 compared metrics.

A side-by-side comparison of Shoulder Innovations, Inc. and TransMedics Group, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of June 21, 2026. The ● marks the stronger figure on each row (cheaper multiple, higher margin/return).

Compare
Shoulder Innovations, Inc. logo
SI
Shoulder Innovations, Inc.
$385M
$18.55Healthcare
TransMedics Group, Inc. logo
TMDX
TransMedics Group, Inc.
$2.72B
$78.79Healthcare

Total return — SI vs TMDX

growth of $100 · last 1y
SI +23.3%TMDX -33.8%SI compounded faster
6080100120Start $1002026$123$66
SI TMDX

SI vs TMDX: by the numbers

  • •TMDX is the larger company ($2.72B vs $385M market cap).
  • •TMDX is profitable (27.04% net margin) while SI runs a net loss (-81.78%).

Metrics side by side

Valuation

MetricSITMDX
P/E ratio—18.03
Forward P/E—38.89
P/S ratio7.114.48●
P/B ratio2.88●5.77
PEG ratio—0.05
EV / EBITDA—23.28
FCF yield—5.31%

Profitability

MetricSITMDX
Gross margin75.48%●59.09%
Operating margin-57.48%14.85%●
Net margin-81.78%27.04%●
ROE-33.14%34.80%●
ROIC-14.80%10.94%●

Growth (annualized)

MetricSITMDX
Revenue CAGR (5Y)—90.79%
Total return CAGR (5Y)—21.48%

Frequently asked

Is SI or TMDX more profitable?
TMDX runs the higher net margin — SI at -81.78% versus TMDX at 27.04%.

Go deeper

Full SI analysisFull TMDX analysisInteractive comparison tool

Dig into the metrics

Shoulder Innovations P/E ratioTransMedics P/E ratioShoulder Innovations dividend yieldTransMedics dividend yieldShoulder Innovations ROETransMedics ROEShoulder Innovations operating marginTransMedics operating marginShoulder Innovations revenue growthTransMedics revenue growthShoulder Innovations free cash flowTransMedics free cash flow

Shoulder Innovations & TransMedics appear in these rankings

Fastest Revenue Growth StocksHighest ROE StocksHighest FCF Yield Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified June 21, 2026.