Sera Prognostics, Inc. (SERA) vs Verrica Pharmaceuticals Inc. (VRCA)

A side-by-side comparison of Sera Prognostics, Inc. and Verrica Pharmaceuticals Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

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Total return — SERA vs VRCA

growth of $100 · dividends reinvested · last 5y
SERA -83.2% (-30.0%/yr)VRCA -95.9% (-47.2%/yr)SERA compounded faster over this window
050100Start $10020222023202420252026$17$4
SERA VRCA

SERA vs VRCA: by the numbers

  • •SERA is the larger company ($78M vs $72M market cap).
  • •Both run net losses; VRCA's is the smaller (-102.84% vs -47475.71% net margin).
  • •VRCA grew revenue faster over the past five years (20.37% vs 9.73% CAGR).

Metrics side by side

Valuation

MetricSERAVRCA
P/S ratio1118.452.39
P/B ratio1.3216.79

Profitability

MetricSERAVRCA
Gross margin-102.47%85.89%
Operating margin-45066.67%-33.56%
Net margin-47475.71%-102.84%
ROE-55.97%-724.01%
ROIC-59.79%-207.23%

Growth (annualized)

MetricSERAVRCA
Revenue CAGR (5Y)9.73%20.37%
Total return CAGR (5Y)-28.91%-48.68%

Frequently asked

Which has grown faster, SERA or VRCA?
Over the past five years, VRCA grew revenue faster — SERA at a 9.73% CAGR versus VRCA at 20.37%.
How have SERA and VRCA total returns compared?
Over the past 5 years, SERA delivered -28.91% and VRCA delivered -48.68% annualized total return. Past performance doesn't predict future results.

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.