Which has grown faster, SCLX or SCYX?

Over the past five years, SCYX grew revenue faster — SCLX at a 3.58% CAGR versus SCYX at 9.78%.

How have SCLX and SCYX total returns compared?

Over the past 5 years, SCLX delivered -59.50% and SCYX delivered -34.13% annualized total return. Past performance doesn't predict future results.

Scilex Holding Company (SCLX) vs SCYNEXIS, Inc. (SCYX)

A side-by-side comparison of Scilex Holding Company and SCYNEXIS, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

SCLX

Scilex Holding Company

$34M

$3.96HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT

SCYX

SCYNEXIS, Inc.

$30M

$4.84HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT

Total return — SCLX vs SCYX

growth of $100 · dividends reinvested · last 6y

SCLX -98.9% (-52.8%/yr)SCYX -92.8% (-35.4%/yr)SCYX compounded faster over this window

Log scale — wide-divergence pair

SCLX SCYX

SCLX vs SCYX: by the numbers

•SCLX is the larger company ($34M vs $30M market cap).
•Both run net losses; SCYX's is the smaller (-53.27% vs -1414.57% net margin).
•SCYX grew revenue faster over the past five years (9.78% vs 3.58% CAGR).

Metrics side by side

Valuation

Metric	SCLX	SCYX
P/S ratio	1.06	1.58
P/B ratio	N/A	0.45

Profitability

Metric	SCLX	SCYX
Gross margin	49.68%	100.00%
Operating margin	-903.52%	-78.03%
Net margin	-1414.57%	-53.27%
ROE	N/A	-15.29%
ROIC	N/A	-32.68%

Growth (annualized)

Metric	SCLX	SCYX
Revenue CAGR (5Y)	3.58%	9.78%
Total return CAGR (5Y)	-59.50%	-34.13%

Frequently asked

Which has grown faster, SCLX or SCYX?: Over the past five years, SCYX grew revenue faster — SCLX at a 3.58% CAGR versus SCYX at 9.78%.
How have SCLX and SCYX total returns compared?: Over the past 5 years, SCLX delivered -59.50% and SCYX delivered -34.13% annualized total return. Past performance doesn't predict future results.

Go deeper

Full SCLX analysis Full SCYX analysis Interactive comparison tool

Dig into the metrics

Scilex ROE SCYNEXIS ROE Scilex operating margin SCYNEXIS operating margin Scilex revenue growth SCYNEXIS revenue growth Scilex free cash flow SCYNEXIS free cash flow

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.