REGENXBIO Inc. (RGNX) vs Shoulder Innovations, Inc. (SI)
A side-by-side comparison of REGENXBIO Inc. and Shoulder Innovations, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.
RGNX
REGENXBIO Inc.
$7.45HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT
SI
Shoulder Innovations, Inc.
$19.14HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT
Total return — RGNX vs SI
growth of $100 · dividends reinvested · last 1yRGNX -8.8% (-8.8%/yr)SI +30.2% (+30.2%/yr)SI compounded faster over this window
RGNX SI
RGNX vs SI: by the numbers
- •SI is the larger company ($397M vs $385M market cap).
- •Both run net losses; SI's is the smaller (-58.33% vs -112.58% net margin).
Metrics side by side
Valuation
| Metric | RGNX | SI |
|---|---|---|
| P/S ratio | 2.21 | 6.61 |
| P/B ratio | 5.37 | 3.19 |
Profitability
| Metric | RGNX | SI |
|---|---|---|
| Gross margin | 88.09% | 77.34% |
| Operating margin | -94.08% | -58.53% |
| Net margin | -112.58% | -58.33% |
| ROE | -273.72% | -28.18% |
| ROIC | -54.00% | -25.26% |
Growth (annualized)
| Metric | RGNX | SI |
|---|---|---|
| Revenue CAGR (5Y) | 1.59% | N/A |
| Total return CAGR (5Y) | -24.15% | N/A |
Go deeper
Dig into the metrics
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.