Regeneron Pharmaceuticals, Inc. (REGN) vs Stryker Corporation (SYK)
A side-by-side comparison of Regeneron Pharmaceuticals, Inc. and Stryker Corporation across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of September 8, 2026. Differences are shown without an overall score or investment verdict.
REGN
Regeneron Pharmaceuticals, Inc.
$810.11HealthcareDelayed quote: Sep 8, 2026, 11:45 AM EDT
SYK
Stryker Corporation
$276.55HealthcareDelayed quote: Sep 8, 2026, 11:45 AM EDT
Total return — REGN vs SYK
growth of $100 · dividends reinvested · last 10yREGN +113.7% (+7.9%/yr)SYK +206.2% (+11.8%/yr)SYK compounded faster over this window
REGN SYK
REGN vs SYK: by the numbers
- •SYK is the larger company ($106.02B vs $83.46B market cap).
- •REGN trades at the lower trailing earnings multiple (20.47 vs 31.41 P/E), one valuation lens rather than an overall verdict.
- •REGN converts more revenue to profit (27.86% vs 14.43% net margin).
- •SYK grew revenue faster over the past five years (9.72% vs 4.64% CAGR).
- •SYK pays the higher dividend yield (1.15% vs 0.45%).
Metrics side by side
Valuation
| Metric | REGN | SYK |
|---|---|---|
| P/E ratio | 20.47 | 31.41 |
| Forward P/E | 15.25 | 20.18 |
| P/S ratio | 5.69 | 4.53 |
| P/B ratio | 2.79 | 4.88 |
| EV / EBITDA | 19.55 | 18.53 |
| FCF yield | 3.98% | 4.02% |
Profitability
| Metric | REGN | SYK |
|---|---|---|
| Gross margin | 84.86% | 65.17% |
| Operating margin | 25.56% | 22.03% |
| Net margin | 27.86% | 14.43% |
| ROE | 13.65% | 15.55% |
| ROIC | 9.19% | 9.82% |
Dividends
| Metric | REGN | SYK |
|---|---|---|
| Dividend yield | 0.45% | 1.15% |
| Payout ratio | 9.15% | 36.06% |
Growth (annualized)
| Metric | REGN | SYK |
|---|---|---|
| Revenue CAGR (5Y) | 4.64% | 9.72% |
| EPS CAGR (5Y) | 5.70% | 14.79% |
| FCF CAGR (5Y) | 15.77% | 9.60% |
| Total return CAGR (5Y) | 4.21% | 2.90% |
Frequently asked
- Which has the lower trailing P/E, REGN or SYK?
- REGN has the lower trailing P/E: REGN trades at 20.47 and SYK at 31.41. P/E is one valuation measure and does not by itself establish which business is cheaper.
- Which has grown faster, REGN or SYK?
- Over the past five years, SYK grew revenue faster — REGN at a 4.64% CAGR versus SYK at 9.72%.
- Does REGN or SYK pay a bigger dividend?
- REGN yields 0.45% and SYK yields 1.15% based on trailing dividends and the latest price.
- Is REGN or SYK more profitable?
- REGN runs the higher net margin — REGN at 27.86% versus SYK at 14.43%.
- How have REGN and SYK total returns compared?
- Over the past 10 years, REGN delivered 7.95% and SYK delivered 11.33% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
Regeneron Pharmaceuticals P/E ratioStryker P/E ratioRegeneron Pharmaceuticals dividend yieldStryker dividend yieldRegeneron Pharmaceuticals ROEStryker ROERegeneron Pharmaceuticals operating marginStryker operating marginRegeneron Pharmaceuticals revenue growthStryker revenue growthRegeneron Pharmaceuticals free cash flowStryker free cash flow
Regeneron Pharmaceuticals & Stryker appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified September 8, 2026.