Regeneron Pharmaceuticals, Inc. (REGN) vs Sanofi (SNY)

A side-by-side comparison of Regeneron Pharmaceuticals, Inc. and Sanofi across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of August 28, 2026. Differences are shown without an overall score or investment verdict.

Compare

Total returnREGN vs SNY

growth of $100 · dividends reinvested · last 10y
REGN +109.8% (+7.7%/yr)SNY +72.2% (+5.6%/yr)REGN compounded faster over this window
100150200250300Start $10020182020202220242026$210$172
REGN SNY

REGN vs SNY: by the numbers

  • SNY is the larger company ($107.47B vs $81.51B market cap).
  • REGN trades at the lower trailing earnings multiple (19.98 vs 80.55 P/E), one valuation lens rather than an overall verdict.
  • REGN converts more revenue to profit (27.86% vs 8.10% net margin).
  • SNY grew revenue faster over the past five years (4.96% vs 4.64% CAGR).
  • SNY pays the higher dividend yield (5.39% vs 0.45%).

Metrics side by side

Valuation

MetricREGNSNY
P/E ratio19.9880.55
Forward P/E14.89N/A
P/S ratio5.551.89
P/B ratio2.721.36
EV / EBITDA19.0710.17
FCF yield4.08%12.72%

Profitability

MetricREGNSNY
Gross margin84.86%73.01%
Operating margin25.56%14.74%
Net margin27.86%8.10%
ROE13.65%5.82%
ROIC9.19%5.42%

Dividends

MetricREGNSNY
Dividend yield0.45%5.39%
Payout ratio8.45%64.36%

Growth (annualized)

MetricREGNSNY
Revenue CAGR (5Y)4.64%4.96%
EPS CAGR (5Y)5.70%-8.92%
FCF CAGR (5Y)15.77%12.83%
Total return CAGR (5Y)4.21%1.38%

Frequently asked

Which has the lower trailing P/E, REGN or SNY?
REGN has the lower trailing P/E: REGN trades at 19.98 and SNY at 80.55. P/E is one valuation measure and does not by itself establish which business is cheaper.
Which has grown faster, REGN or SNY?
Over the past five years, SNY grew revenue faster — REGN at a 4.64% CAGR versus SNY at 4.96%.
Does REGN or SNY pay a bigger dividend?
REGN yields 0.45% and SNY yields 5.39% based on trailing dividends and the latest price.
Is REGN or SNY more profitable?
REGN runs the higher net margin — REGN at 27.86% versus SNY at 8.10%.
How have REGN and SNY total returns compared?
Over the past 10 years, REGN delivered 7.30% and SNY delivered 5.69% annualized total return. Past performance doesn't predict future results.

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified August 28, 2026.