Quantum-Si incorporated (QSI) vs Upstream Bio, Inc. (UPB)
A side-by-side comparison of Quantum-Si incorporated and Upstream Bio, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.
QSI
Quantum-Si incorporated
$1.22HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT
UPB
Upstream Bio, Inc.
$4.59HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT
Total return — QSI vs UPB
growth of $100 · dividends reinvested · last 2yQSI +55.2% (+24.6%/yr)UPB -78.0% (-53.0%/yr)QSI compounded faster over this window
Log scale — wide-divergence pair
QSI UPB
QSI vs UPB: by the numbers
- •UPB is the larger company ($250M vs $241M market cap).
- •Both run net losses; UPB's is the smaller (-4955.67% vs -6138.26% net margin).
Metrics side by side
Valuation
| Metric | QSI | UPB |
|---|---|---|
| P/S ratio | 150.37 | 79.10 |
| P/B ratio | 1.34 | 0.92 |
Profitability
| Metric | QSI | UPB |
|---|---|---|
| Gross margin | 47.33% | 98.45% |
| Operating margin | -3996.72% | -5618.82% |
| Net margin | -6138.26% | -4955.67% |
| ROE | -54.67% | -57.76% |
| ROIC | -51.87% | -62.51% |
Growth (annualized)
| Metric | QSI | UPB |
|---|---|---|
| Total return CAGR (5Y) | -31.06% | N/A |
Go deeper
Dig into the metrics
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.