QuidelOrtho Corporation (QDEL) vs SI-BONE, Inc. (SIBN)
A side-by-side comparison of QuidelOrtho Corporation and SI-BONE, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.
QDEL
QuidelOrtho Corporation
$12.57HealthcareDelayed quote: Oct 6, 2026, 1:15 PM EDT
SIBN
SI-BONE, Inc.
$19.45HealthcareDelayed quote: Oct 6, 2026, 1:15 PM EDT
Total return — QDEL vs SIBN
growth of $100 · dividends reinvested · last 8yQDEL -82.1% (-19.3%/yr)SIBN -1.2% (-0.2%/yr)SIBN compounded faster over this window
Log scale — wide-divergence pair
QDEL SIBN
QDEL vs SIBN: by the numbers
- •SIBN is the larger company ($863M vs $857M market cap).
- •Both run net losses; SIBN's is the smaller (-6.85% vs -39.20% net margin).
- •SIBN grew revenue faster over the past five years (20.20% vs 7.14% CAGR).
Metrics side by side
Valuation
| Metric | QDEL | SIBN |
|---|---|---|
| Forward P/E | 16.27 | N/A |
| P/S ratio | 0.32 | 4.04 |
| P/B ratio | 0.48 | 4.73 |
Profitability
| Metric | QDEL | SIBN |
|---|---|---|
| Gross margin | 44.60% | 79.53% |
| Operating margin | -30.67% | -8.31% |
| Net margin | -39.20% | -6.85% |
| ROE | -59.07% | -8.03% |
| ROIC | -16.05% | -7.88% |
Growth (annualized)
| Metric | QDEL | SIBN |
|---|---|---|
| Revenue CAGR (5Y) | 7.14% | 20.20% |
| Total return CAGR (5Y) | -38.12% | -1.46% |
Frequently asked
- Which has grown faster, QDEL or SIBN?
- Over the past five years, SIBN grew revenue faster — QDEL at a 7.14% CAGR versus SIBN at 20.20%.
- How have QDEL and SIBN total returns compared?
- Over the past 5 years, QDEL delivered -38.12% and SIBN delivered -1.46% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
QuidelOrtho ROESI-BONE ROEQuidelOrtho operating marginSI-BONE operating marginQuidelOrtho revenue growthSI-BONE revenue growthQuidelOrtho free cash flowSI-BONE free cash flow
QuidelOrtho & SI-BONE appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.