Pyxis Oncology, Inc. (PYXS) vs Tonix Pharmaceuticals Holding Corp. (TNXP)

A side-by-side comparison of Pyxis Oncology, Inc. and Tonix Pharmaceuticals Holding Corp. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

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Total return — PYXS vs TNXP

growth of $100 · dividends reinvested · last 5y
PYXS -83.0% (-29.9%/yr)TNXP -100.0% (-87.3%/yr)PYXS compounded faster over this window
Log scale — wide-divergence pair
0001101001kStart $10020222023202420252026$17$0
PYXS TNXP

PYXS vs TNXP: by the numbers

  • •PYXS is the larger company ($128M vs $123M market cap).
  • •Both run net losses; TNXP's is the smaller (-548.64% vs -803.83% net margin).

Metrics side by side

Valuation

MetricPYXSTNXP
P/S ratio11.594.21
P/B ratio11.190.55

Profitability

MetricPYXSTNXP
Gross margin82.77%34.65%
Operating margin-609.18%-959.05%
Net margin-803.83%-548.64%
ROE-775.59%-71.83%
ROIC-314.66%-74.08%

Growth (annualized)

MetricPYXSTNXP
Total return CAGR (5Y)N/A-87.55%

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.