Palvella Therapeutics, Inc. (PVLA) vs Sarepta Therapeutics, Inc. (SRPT)

A side-by-side comparison of Palvella Therapeutics, Inc. and Sarepta Therapeutics, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

Compare
Palvella Therapeutics, Inc. logo
PVLA
Palvella Therapeutics, Inc.
$1.84B
$128.00HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT
Sarepta Therapeutics, Inc. logo
SRPT
Sarepta Therapeutics, Inc.
$1.83B
$17.31HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT

Total return — PVLA vs SRPT

growth of $100 · dividends reinvested · last 2y
PVLA +677.4% (+178.8%/yr)SRPT -86.1% (-62.7%/yr)PVLA compounded faster over this window
Log scale — wide-divergence pair
101001kStart $10020252026$777$14
PVLA SRPT

PVLA vs SRPT: by the numbers

  • •PVLA is the larger company ($1.84B vs $1.83B market cap).
  • •Both run net losses; PVLA's is the smaller (0.00% vs -6.93% net margin).

Metrics side by side

Valuation

MetricPVLASRPT
Forward P/EN/A5.38
P/S ratioN/A0.93
P/B ratio8.471.20

Profitability

MetricPVLASRPT
Gross margin0.00%58.56%
Operating margin0.00%-29.92%
Net margin0.00%-6.93%
ROE-28.45%-8.95%
ROIC-23.90%-5.33%

Growth (annualized)

MetricPVLASRPT
Revenue CAGR (5Y)N/A26.90%
Total return CAGR (5Y)N/A-28.74%

Go deeper

Full PVLA analysisFull SRPT analysisInteractive comparison tool

Dig into the metrics

Palvella Therapeutics ROESarepta Therapeutics ROEPalvella Therapeutics operating marginSarepta Therapeutics operating marginPalvella Therapeutics revenue growthSarepta Therapeutics revenue growthPalvella Therapeutics free cash flowSarepta Therapeutics free cash flow

Palvella Therapeutics & Sarepta Therapeutics appear in these rankings

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Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.