Personalis, Inc. (PSNL) vs uniQure N.V. (QURE)

A side-by-side comparison of Personalis, Inc. and uniQure N.V. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

Compare

Total return — PSNL vs QURE

growth of $100 · dividends reinvested · last 7y
PSNL -42.4% (-7.6%/yr)QURE -71.8% (-16.5%/yr)PSNL compounded faster over this window
050100150Start $100202120232025$58$28
PSNL QURE

PSNL vs QURE: by the numbers

  • •PSNL is the larger company ($1.70B vs $1.61B market cap).
  • •Both run net losses; PSNL's is the smaller (-153.84% vs -1350.73% net margin).
  • •Both shrank revenue over the past five years; PSNL's decline was smaller (-3.33% vs -48.20% CAGR).

Metrics side by side

Valuation

MetricPSNLQURE
P/S ratio24.3886.46
P/B ratio7.224.98

Profitability

MetricPSNLQURE
Gross margin22.65%89.53%
Operating margin-126.43%-1166.77%
Net margin-153.84%-1350.73%
ROE-45.58%-77.83%
ROIC-42.87%-22.55%

Growth (annualized)

MetricPSNLQURE
Revenue CAGR (5Y)-3.33%-48.20%
Total return CAGR (5Y)-1.75%-6.16%

Frequently asked

Which has grown faster, PSNL or QURE?
Neither grew: over the past five years both shrank revenue, with PSNL's decline the smaller — PSNL at a -3.33% CAGR versus QURE at -48.20%.
How have PSNL and QURE total returns compared?
Over the past 5 years, PSNL delivered -1.75% and QURE delivered -6.16% annualized total return. Past performance doesn't predict future results.

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.