Prothena Corporation plc (PRTA) vs YD Bio Limited Ordinary Shares (YDES)
A side-by-side comparison of Prothena Corporation plc and YD Bio Limited Ordinary Shares across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.
PRTA
Prothena Corporation plc
$8.02HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT
YDES
YD Bio Limited Ordinary Shares
$6.15HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT
Total return — PRTA vs YDES
growth of $100 · dividends reinvested · last 1yPRTA +17.6% (+17.6%/yr)YDES -40.9% (-40.9%/yr)PRTA compounded faster over this window
PRTA YDES
PRTA vs YDES: by the numbers
- •YDES is the larger company ($436M vs $420M market cap).
- •Both run net losses; PRTA's is the smaller (-80.67% vs -1392.61% net margin).
Metrics side by side
Valuation
| Metric | PRTA | YDES |
|---|---|---|
| Forward P/E | 72.91 | N/A |
| P/S ratio | 7.70 | N/A |
| P/B ratio | 1.46 | N/A |
Profitability
| Metric | PRTA | YDES |
|---|---|---|
| Gross margin | 61.77% | -7.06% |
| Operating margin | -1905.82% | -883.31% |
| Net margin | -80.67% | -1392.61% |
| ROE | -15.33% | -66.49% |
| ROIC | -21.36% | N/A |
Growth (annualized)
| Metric | PRTA | YDES |
|---|---|---|
| Revenue CAGR (5Y) | 62.57% | N/A |
| Total return CAGR (5Y) | -35.08% | N/A |
Go deeper
Dig into the metrics
Prothena ROEYD Bio Limited Ordinary Shares ROEProthena operating marginYD Bio Limited Ordinary Shares operating marginProthena revenue growthYD Bio Limited Ordinary Shares revenue growthProthena free cash flowYD Bio Limited Ordinary Shares free cash flow
Prothena & YD Bio Limited Ordinary Shares appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.