Which has the lower trailing P/E, PFE or TMO?

TMO has the lower trailing P/E: PFE trades at 36.63 and TMO at 32.80. P/E is one valuation measure and does not by itself establish which business is cheaper.

Which has grown faster, PFE or TMO?

Over the past five years, PFE grew revenue faster — PFE at a 6.29% CAGR versus TMO at 5.00%.

Does PFE or TMO pay a bigger dividend?

PFE yields 6.19% and TMO yields 0.30% based on trailing dividends and the latest price.

Is PFE or TMO more profitable?

TMO runs the higher net margin — PFE at 6.81% versus TMO at 15.06%.

How have PFE and TMO total returns compared?

Over the past 10 years, PFE delivered 3.17% and TMO delivered 15.81% annualized total return. Past performance doesn't predict future results.

Pfizer Inc. (PFE) vs Thermo Fisher Scientific Inc. (TMO)

A side-by-side comparison of Pfizer Inc. and Thermo Fisher Scientific Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of September 10, 2026. Differences are shown without an overall score or investment verdict.

PFE

Pfizer Inc.

$157.99B

$27.72HealthcareDelayed quote: Sep 11, 2026, 4:01 PM EDT

TMO

Thermo Fisher Scientific Inc.

$226.62B

$609.82HealthcareDelayed quote: Sep 11, 2026, 4:00 PM EDT

Total return — PFE vs TMO

growth of $100 · dividends reinvested · last 10y

PFE +37.3% (+3.2%/yr)TMO +314.9% (+15.3%/yr)TMO compounded faster over this window

PFE TMO

PFE vs TMO: by the numbers

•TMO is the larger company ($226.62B vs $157.99B market cap).
•TMO trades at the lower trailing earnings multiple (32.80 vs 36.63 P/E), one valuation lens rather than an overall verdict.
•TMO converts more revenue to profit (15.06% vs 6.81% net margin).
•PFE grew revenue faster over the past five years (6.29% vs 5.00% CAGR).
•PFE pays the higher dividend yield (6.19% vs 0.30%).

Metrics side by side

Valuation

Metric	PFE	TMO
P/E ratio	36.63	32.80
Forward P/E	9.32	24.29
P/S ratio	2.48	4.89
P/B ratio	1.85	4.30
EV / EBITDA	10.15	25.25
FCF yield	6.95%	3.23%

Profitability

Metric	PFE	TMO
Gross margin	71.32%	40.37%
Operating margin	25.08%	17.69%
Net margin	6.81%	15.06%
ROE	5.09%	13.25%
ROIC	9.33%	7.44%

Dividends

Metric	PFE	TMO
Dividend yield	6.19%	0.30%
Payout ratio	227.27%	9.68%

Growth (annualized)

Metric	PFE	TMO
Revenue CAGR (5Y)	6.29%	5.00%
EPS CAGR (5Y)	-3.78%	1.99%
FCF CAGR (5Y)	-3.11%	-1.83%
Total return CAGR (5Y)	-4.68%	1.55%

Frequently asked

Which has the lower trailing P/E, PFE or TMO?: TMO has the lower trailing P/E: PFE trades at 36.63 and TMO at 32.80. P/E is one valuation measure and does not by itself establish which business is cheaper.
Which has grown faster, PFE or TMO?: Over the past five years, PFE grew revenue faster — PFE at a 6.29% CAGR versus TMO at 5.00%.
Does PFE or TMO pay a bigger dividend?: PFE yields 6.19% and TMO yields 0.30% based on trailing dividends and the latest price.
Is PFE or TMO more profitable?: TMO runs the higher net margin — PFE at 6.81% versus TMO at 15.06%.
How have PFE and TMO total returns compared?: Over the past 10 years, PFE delivered 3.17% and TMO delivered 15.81% annualized total return. Past performance doesn't predict future results.

Go deeper

Full PFE analysis Full TMO analysis Interactive comparison tool

Dig into the metrics

Pfizer P/E ratio Thermo Fisher Scientific P/E ratio Pfizer dividend yield Thermo Fisher Scientific dividend yield Pfizer ROE Thermo Fisher Scientific ROE Pfizer operating margin Thermo Fisher Scientific operating margin Pfizer revenue growth Thermo Fisher Scientific revenue growth Pfizer free cash flow Thermo Fisher Scientific free cash flow

Pfizer & Thermo Fisher Scientific appear in these rankings

Highest Dividend Yield Stocks Highest FCF Yield Stocks Highest 10-Year Total Return Stocks Largest Companies by Market Cap

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified September 10, 2026.