Is PFE or TMO cheaper?

On trailing earnings, PFE is cheaper: PFE trades at a 20.01 P/E and TMO at 25.80.

Which has grown faster, PFE or TMO?

Over the past five years, PFE grew revenue faster — PFE at a 8.22% CAGR versus TMO at 6.68%.

Does PFE or TMO pay a bigger dividend?

PFE yields 6.56% and TMO yields 0.28% based on trailing dividends and the latest price.

Is PFE or TMO more profitable?

TMO runs the higher net margin — PFE at 11.83% versus TMO at 15.18%.

Which has been the better investment, PFE or TMO?

Over the past 10-year, TMO delivered the higher annualized total return — PFE at 2.13% versus TMO at 12.26%. Past performance doesn't predict future results.

Pfizer Inc. (PFE) vs Thermo Fisher Scientific Inc. (TMO)

PFE leads on 11 of 16 compared metrics.

A side-by-side comparison of Pfizer Inc. and Thermo Fisher Scientific Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of June 13, 2026. The ● marks the stronger figure on each row (cheaper multiple, higher margin/return).

Thermo Fisher Scientific Inc.

$174.42B

$469.34Healthcare

Total return — PFE vs TMO

growth of $100 · last 30y

PFE +128.5%TMO +1154.9%TMO compounded faster

Log scale — wide-divergence pair

PFE TMO

PFE vs TMO: by the numbers

•TMO is the larger company ($174.42B vs $149.38B market cap).
•PFE trades at the lower earnings multiple (20.01 vs 25.80 P/E).
•TMO converts more revenue to profit (15.18% vs 11.83% net margin).
•PFE grew revenue faster over the past five years (8.22% vs 6.68% CAGR).
•PFE pays the higher dividend yield (6.56% vs 0.28%).

Which is better, PFE or TMO?

Metric tally: PFE 11 · TMO 5

It depends on what you're optimizing for:

ValuePFE(lower P/E)

GrowthPFE(faster 5Y revenue CAGR)

IncomePFE(higher dividend yield)

QualityPFE(higher ROIC)

Valuation

Metric	PFE	TMO
P/E ratio	20.01●	25.80
Forward P/E	9.25●	17.26
P/S ratio	2.37●	3.87
P/B ratio	1.67●	3.37
PEG ratio	—	4.51
EV / EBITDA	12.72●	19.26
FCF yield	6.31%●	3.86%

Profitability

Metric	PFE	TMO
Gross margin	69.35%●	39.41%
Operating margin	23.45%●	17.76%
Net margin	11.83%	15.18%●
ROE	8.31%	13.21%●
ROIC	8.84%●	7.58%

Dividends

Metric	PFE	TMO
Dividend yield	6.56%●	0.28%
Payout ratio	126.47%	7.48%

Growth (annualized)

Metric	PFE	TMO
Revenue CAGR (5Y)	8.22%●	6.68%
EPS CAGR (5Y)	-3.78%	1.99%●
FCF CAGR (5Y)	-3.79%	-0.19%●
Total return CAGR (5Y)	-3.33%	0.45%●

Frequently asked

Which is better, PFE or TMO?: It depends on your goal. value: PFE (lower P/E); growth: PFE (faster 5Y revenue CAGR); income: PFE (higher dividend yield); quality: PFE (higher ROIC). Across all compared metrics, PFE leads 11 to 5.
Is PFE or TMO cheaper?: On trailing earnings, PFE is cheaper: PFE trades at a 20.01 P/E and TMO at 25.80.
Which has grown faster, PFE or TMO?: Over the past five years, PFE grew revenue faster — PFE at a 8.22% CAGR versus TMO at 6.68%.
Does PFE or TMO pay a bigger dividend?: PFE yields 6.56% and TMO yields 0.28% based on trailing dividends and the latest price.
Is PFE or TMO more profitable?: TMO runs the higher net margin — PFE at 11.83% versus TMO at 15.18%.
Which has been the better investment, PFE or TMO?: Over the past 10-year, TMO delivered the higher annualized total return — PFE at 2.13% versus TMO at 12.26%. Past performance doesn't predict future results.

Go deeper

Full PFE analysis Full TMO analysis Interactive comparison tool

Dig into the metrics

Pfizer P/E ratio Thermo Fisher Scientific P/E ratio Pfizer dividend yield Thermo Fisher Scientific dividend yield Pfizer ROE Thermo Fisher Scientific ROE Pfizer operating margin Thermo Fisher Scientific operating margin Pfizer revenue growth Thermo Fisher Scientific revenue growth Pfizer free cash flow Thermo Fisher Scientific free cash flow

Pfizer & Thermo Fisher Scientific appear in these rankings

Highest Dividend Yield Stocks Highest FCF Yield Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified June 13, 2026.