Which has the lower trailing P/E, PFE or SYK?

PFE has the lower trailing P/E: PFE trades at 19.09 and SYK at 33.75. P/E is one valuation measure and does not by itself establish which business is cheaper.

Which has grown faster, PFE or SYK?

Over the past five years, SYK grew revenue faster — PFE at a 8.22% CAGR versus SYK at 9.72%.

Does PFE or SYK pay a bigger dividend?

PFE yields 6.88% and SYK yields 1.07% based on trailing dividends and the latest price.

Is PFE or SYK more profitable?

SYK runs the higher net margin — PFE at 11.83% versus SYK at 14.43%.

How have PFE and SYK total returns compared?

Over the past 10 years, PFE delivered 1.38% and SYK delivered 12.07% annualized total return. Past performance doesn't predict future results.

Pfizer Inc. (PFE) vs Stryker Corporation (SYK)

A side-by-side comparison of Pfizer Inc. and Stryker Corporation across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of August 1, 2026. Differences are shown without an overall score or investment verdict.

PFE

Pfizer Inc.

$142.54B

$25.01HealthcareAt close: Jul 31, 2026, 4:00 PM ET

SYK

Stryker Corporation

$124.86B

$325.70HealthcareDelayed quote: Jul 31, 2026, 4:00 PM EDT

Total return — PFE vs SYK

growth of $100 · dividends reinvested · last 30y

PFE +555.6%SYK +6840.2%SYK compounded faster

Log scale — wide-divergence pair

PFE SYK

PFE vs SYK: by the numbers

•PFE is the larger company ($142.54B vs $124.86B market cap).
•PFE trades at the lower trailing earnings multiple (19.09 vs 33.75 P/E), one valuation lens rather than an overall verdict.
•SYK converts more revenue to profit (14.43% vs 11.83% net margin).
•SYK grew revenue faster over the past five years (9.72% vs 8.22% CAGR).
•PFE pays the higher dividend yield (6.88% vs 1.07%).

Metrics side by side

Valuation

Metric	PFE	SYK
P/E ratio	19.09	33.75
Forward P/E	8.50	21.73
P/S ratio	2.26	4.87
P/B ratio	1.59	2.62
PEG ratio	N/A	5.16
EV / EBITDA	9.81	20.56
FCF yield	6.62%	3.63%

Profitability

Metric	PFE	SYK
Gross margin	69.35%	65.17%
Operating margin	23.45%	22.03%
Net margin	11.83%	14.43%
ROE	8.31%	7.78%
ROIC	8.84%	8.53%

Dividends

Metric	PFE	SYK
Dividend yield	6.88%	1.07%
Payout ratio	126.47%	40.99%

Growth (annualized)

Metric	PFE	SYK
Revenue CAGR (5Y)	8.22%	9.72%
EPS CAGR (5Y)	-3.78%	14.79%
FCF CAGR (5Y)	-3.79%	11.01%
Total return CAGR (5Y)	-5.29%	4.83%

Frequently asked

Which has the lower trailing P/E, PFE or SYK?: PFE has the lower trailing P/E: PFE trades at 19.09 and SYK at 33.75. P/E is one valuation measure and does not by itself establish which business is cheaper.
Which has grown faster, PFE or SYK?: Over the past five years, SYK grew revenue faster — PFE at a 8.22% CAGR versus SYK at 9.72%.
Does PFE or SYK pay a bigger dividend?: PFE yields 6.88% and SYK yields 1.07% based on trailing dividends and the latest price.
Is PFE or SYK more profitable?: SYK runs the higher net margin — PFE at 11.83% versus SYK at 14.43%.
How have PFE and SYK total returns compared?: Over the past 10 years, PFE delivered 1.38% and SYK delivered 12.07% annualized total return. Past performance doesn't predict future results.

Go deeper

Full PFE analysis Full SYK analysis Interactive comparison tool

Dig into the metrics

Pfizer P/E ratio Stryker P/E ratio Pfizer dividend yield Stryker dividend yield Pfizer ROE Stryker ROE Pfizer operating margin Stryker operating margin Pfizer revenue growth Stryker revenue growth Pfizer free cash flow Stryker free cash flow

Pfizer & Stryker appear in these rankings

Highest Dividend Yield Stocks 25+ Year Dividend Growers Highest FCF Yield Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified August 1, 2026.