Is PFE or SYK cheaper?

On trailing earnings, PFE is cheaper: PFE trades at a 19.85 P/E and SYK at 35.95.

Which has grown faster, PFE or SYK?

Over the past five years, SYK grew revenue faster — PFE at a 8.22% CAGR versus SYK at 11.42%.

Does PFE or SYK pay a bigger dividend?

PFE yields 6.62% and SYK yields 1.11% based on trailing dividends and the latest price.

Is PFE or SYK more profitable?

SYK runs the higher net margin — PFE at 11.83% versus SYK at 13.21%.

Which has been the better investment, PFE or SYK?

Over the past 10-year, SYK delivered the higher annualized total return — PFE at 2.25% versus SYK at 11.71%. Past performance doesn't predict future results.

Pfizer Inc. (PFE) vs Stryker Corporation (SYK)

PFE leads on 10 of 16 compared metrics.

A side-by-side comparison of Pfizer Inc. and Stryker Corporation across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of June 16, 2026. The ● marks the stronger figure on each row (cheaper multiple, higher margin/return).

Total return — PFE vs SYK

growth of $100 · last 30y

PFE +120.2%SYK +4798.7%SYK compounded faster

Log scale — wide-divergence pair

PFE SYK

PFE vs SYK: by the numbers

•PFE is the larger company ($148.76B vs $119.06B market cap).
•PFE trades at the lower earnings multiple (19.85 vs 35.95 P/E).
•SYK converts more revenue to profit (13.21% vs 11.83% net margin).
•SYK grew revenue faster over the past five years (11.42% vs 8.22% CAGR).
•PFE pays the higher dividend yield (6.62% vs 1.11%).

Which is better, PFE or SYK?

Metric tally: PFE 10 · SYK 6

It depends on what you're optimizing for:

ValuePFE(lower P/E)

GrowthSYK(faster 5Y revenue CAGR)

IncomePFE(higher dividend yield)

QualityPFE(higher ROIC)

Metrics side by side

Valuation

Metric	PFE	SYK
P/E ratio	19.85●	35.95
Forward P/E	9.21●	18.56
P/S ratio	2.35●	4.75
P/B ratio	1.65●	5.22
PEG ratio	—	5.16
EV / EBITDA	12.64●	21.49
FCF yield	6.37%●	3.81%

Profitability

Metric	PFE	SYK
Gross margin	69.35%●	63.67%
Operating margin	23.45%●	21.34%
Net margin	11.83%	13.21%●
ROE	8.31%	14.52%●
ROIC	8.84%●	8.53%

Dividends

Metric	PFE	SYK
Dividend yield	6.62%●	1.11%
Payout ratio	126.47%	40.52%

Growth (annualized)

Metric	PFE	SYK
Revenue CAGR (5Y)	8.22%	11.42%●
EPS CAGR (5Y)	-3.78%	14.79%●
FCF CAGR (5Y)	-3.79%	11.01%●
Total return CAGR (5Y)	-3.00%	4.98%●

Frequently asked

Which is better, PFE or SYK?: It depends on your goal. value: PFE (lower P/E); growth: SYK (faster 5Y revenue CAGR); income: PFE (higher dividend yield); quality: PFE (higher ROIC). Across all compared metrics, PFE leads 10 to 6.
Is PFE or SYK cheaper?: On trailing earnings, PFE is cheaper: PFE trades at a 19.85 P/E and SYK at 35.95.
Which has grown faster, PFE or SYK?: Over the past five years, SYK grew revenue faster — PFE at a 8.22% CAGR versus SYK at 11.42%.
Does PFE or SYK pay a bigger dividend?: PFE yields 6.62% and SYK yields 1.11% based on trailing dividends and the latest price.
Is PFE or SYK more profitable?: SYK runs the higher net margin — PFE at 11.83% versus SYK at 13.21%.
Which has been the better investment, PFE or SYK?: Over the past 10-year, SYK delivered the higher annualized total return — PFE at 2.25% versus SYK at 11.71%. Past performance doesn't predict future results.

Go deeper

Full PFE analysis Full SYK analysis Interactive comparison tool

Dig into the metrics

Pfizer P/E ratio Stryker P/E ratio Pfizer dividend yield Stryker dividend yield Pfizer ROE Stryker ROE Pfizer operating margin Stryker operating margin Pfizer revenue growth Stryker revenue growth Pfizer free cash flow Stryker free cash flow

Pfizer & Stryker appear in these rankings

Highest Dividend Yield Stocks Highest FCF Yield Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified June 16, 2026.