Pfizer Inc. (PFE) vs State Street SPDR S&P 500 ETF (SPY)

Over the past 10 years, PFE lagged SPY — 3.17% vs 15.36% annualized total return (price plus dividends).

A side-by-side comparison of Pfizer Inc. and State Street SPDR S&P 500 ETF across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of September 10, 2026. Differences are shown without an overall score or investment verdict.

Compare

Total returnPFE vs SPY

growth of $100 · dividends reinvested · last 10y
PFE +37.3% (+3.2%/yr)SPY +323.5% (+15.5%/yr)SPY compounded faster over this window
100200300400Start $10020182020202220242026$137$424
PFE SPY

Metrics side by side

Did PFE beat SPY?

Over the past 10 years, PFE lagged SPY — 3.17% vs 15.36% annualized total return (price plus dividends).

Total return (annualized)

MetricPFESPY
Total return (1Y)20.36%17.49%
Total return CAGR (3Y)-0.53%20.82%
Total return CAGR (5Y)-4.68%12.73%
Total return CAGR (10Y)3.17%15.36%

SPY is an index fund, so valuation, profitability, and per-company growth metrics don't apply — the head-to-head here is total return (price plus reinvested dividends).

Frequently asked

Has PFE beaten SPY?
Over the past 10 years, PFE lagged SPY — 3.17% vs 15.36% annualized total return (price plus dividends).

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified September 10, 2026.