Pfizer Inc. (PFE) vs State Street SPDR S&P 500 ETF (SPY)

Over the past 10 years, PFE lagged SPY — 1.55% vs 14.89% annualized total return (price plus dividends).

A side-by-side comparison of Pfizer Inc. and State Street SPDR S&P 500 ETF across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of July 28, 2026. Differences are shown without an overall score or investment verdict.

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Different business models: PFE is classified in Healthcare; SPY is classified in Financial Services. Margin, capital intensity, and valuation differences should be interpreted in that sector context.

Total returnPFE vs SPY

growth of $100 · dividends reinvested · last 30y
PFE +562.5%SPY +1866.7%SPY compounded faster
05001k2k2kStart $100200120062011201620212026$662$1,967
PFE SPY

Metrics side by side

Did PFE beat SPY?

Over the past 10 years, PFE lagged SPY — 1.55% vs 14.89% annualized total return (price plus dividends).

Total return (annualized)

MetricPFESPY
Total return (1Y)11.28%17.32%
Total return CAGR (3Y)-5.26%18.85%
Total return CAGR (5Y)-5.21%12.50%
Total return CAGR (10Y)1.55%14.89%

SPY is an index fund, so valuation, profitability, and per-company growth metrics don't apply — the head-to-head here is total return (price plus reinvested dividends).

Frequently asked

Has PFE beaten SPY?
Over the past 10 years, PFE lagged SPY — 1.55% vs 14.89% annualized total return (price plus dividends).

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified July 28, 2026.