Which has the lower trailing P/E, PFE or RHHBY?

RHHBY has the lower trailing P/E: PFE trades at 37.39 and RHHBY at 16.15. P/E is one valuation measure and does not by itself establish which business is cheaper.

Which has grown faster, PFE or RHHBY?

Over the past five years, PFE grew revenue faster — PFE at a 6.29% CAGR versus RHHBY at 3.94%.

Does PFE or RHHBY pay a bigger dividend?

PFE yields 6.08% and RHHBY yields 2.75% based on trailing dividends and the latest price.

Is PFE or RHHBY more profitable?

RHHBY runs the higher net margin — PFE at 6.81% versus RHHBY at 20.33%.

How have PFE and RHHBY total returns compared?

Over the past 10 years, PFE delivered 3.15% and RHHBY delivered 9.59% annualized total return. Past performance doesn't predict future results.

Pfizer Inc. (PFE) vs Roche Holding AG (RHHBY)

A side-by-side comparison of Pfizer Inc. and Roche Holding AG across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of August 27, 2026. Differences are shown without an overall score or investment verdict.

PFE

Pfizer Inc.

$159.64B

$28.01HealthcareDelayed quote: Aug 27, 2026, 4:00 PM EDT

RHHBY

Roche Holding AG

$359.46B

$56.39HealthcareDelayed quote: Aug 27, 2026, 4:00 PM EDT

Total return — PFE vs RHHBY

growth of $100 · dividends reinvested · last 10y

PFE +35.3% (+3.1%/yr)RHHBY +158.1% (+9.9%/yr)RHHBY compounded faster over this window

PFE RHHBY

PFE vs RHHBY: by the numbers

•RHHBY is the larger company ($359.46B vs $159.64B market cap).
•RHHBY trades at the lower trailing earnings multiple (16.15 vs 37.39 P/E), one valuation lens rather than an overall verdict.
•RHHBY converts more revenue to profit (20.33% vs 6.81% net margin).
•PFE grew revenue faster over the past five years (6.29% vs 3.94% CAGR).
•PFE pays the higher dividend yield (6.08% vs 2.75%).

Metrics side by side

Valuation

Metric	PFE	RHHBY
P/E ratio	37.39	16.15
Forward P/E	9.52	22.83
P/S ratio	2.53	4.53
P/B ratio	1.89	9.06
EV / EBITDA	10.30	14.21
FCF yield	6.81%	4.69%

Profitability

Metric	PFE	RHHBY
Gross margin	71.32%	73.73%
Operating margin	25.08%	29.16%
Net margin	6.81%	20.33%
ROE	5.09%	38.06%
ROIC	9.33%	19.71%

Dividends

Metric	PFE	RHHBY
Dividend yield	6.08%	2.75%
Payout ratio	126.47%	60.81%

Growth (annualized)

Metric	PFE	RHHBY
Revenue CAGR (5Y)	6.29%	3.94%
EPS CAGR (5Y)	-3.78%	1.54%
FCF CAGR (5Y)	-3.11%	5.54%
Total return CAGR (5Y)	-4.87%	5.84%

Frequently asked

Which has the lower trailing P/E, PFE or RHHBY?: RHHBY has the lower trailing P/E: PFE trades at 37.39 and RHHBY at 16.15. P/E is one valuation measure and does not by itself establish which business is cheaper.
Which has grown faster, PFE or RHHBY?: Over the past five years, PFE grew revenue faster — PFE at a 6.29% CAGR versus RHHBY at 3.94%.
Does PFE or RHHBY pay a bigger dividend?: PFE yields 6.08% and RHHBY yields 2.75% based on trailing dividends and the latest price.
Is PFE or RHHBY more profitable?: RHHBY runs the higher net margin — PFE at 6.81% versus RHHBY at 20.33%.
How have PFE and RHHBY total returns compared?: Over the past 10 years, PFE delivered 3.15% and RHHBY delivered 9.59% annualized total return. Past performance doesn't predict future results.

Go deeper

Full PFE analysis Full RHHBY analysis Interactive comparison tool

Dig into the metrics

Pfizer P/E ratio Roche Holding AG P/E ratio Pfizer dividend yield Roche Holding AG dividend yield Pfizer ROE Roche Holding AG ROE Pfizer operating margin Roche Holding AG operating margin Pfizer revenue growth Roche Holding AG revenue growth Pfizer free cash flow Roche Holding AG free cash flow

Pfizer & Roche Holding AG appear in these rankings

Highest Dividend Yield Stocks Highest ROE Stocks Highest ROIC Stocks Highest FCF Yield Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified August 27, 2026.