Penumbra, Inc. (PEN) vs Tempus AI, Inc. (TEM)
A side-by-side comparison of Penumbra, Inc. and Tempus AI, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of August 28, 2026. Differences are shown without an overall score or investment verdict.
PEN
Penumbra, Inc.
$321.00HealthcareDelayed quote: Aug 27, 2026, 4:00 PM EDT
TEM
Tempus AI, Inc.
$70.69HealthcareDelayed quote: Aug 27, 2026, 4:00 PM EDT
Total return — PEN vs TEM
growth of $100 · dividends reinvested · last 2yPEN +70.9% (+30.7%/yr)TEM +75.6% (+32.5%/yr)TEM compounded faster over this window
PEN TEM
PEN vs TEM: by the numbers
- •PEN is the larger company ($12.64B vs $12.38B market cap).
- •PEN is profitable (10.67% net margin) while TEM runs a net loss (-17.77%).
- •TEM grew revenue faster over the past five years (38.24% vs 17.52% CAGR).
Metrics side by side
Valuation
| Metric | PEN | TEM |
|---|---|---|
| P/E ratio | 78.87 | N/A |
| Forward P/E | 68.18 | N/A |
| P/S ratio | 8.44 | 9.00 |
| P/B ratio | 8.30 | 28.98 |
| EV / EBITDA | 62.16 | N/A |
| FCF yield | 1.70% | N/A |
Profitability
| Metric | PEN | TEM |
|---|---|---|
| Gross margin | 67.84% | 63.98% |
| Operating margin | 12.45% | -19.76% |
| Net margin | 10.67% | -17.77% |
| ROE | 10.49% | -57.18% |
| ROIC | 8.48% | -14.34% |
Growth (annualized)
| Metric | PEN | TEM |
|---|---|---|
| Revenue CAGR (5Y) | 17.52% | 38.24% |
| EPS CAGR (5Y) | 21.94% | N/A |
| FCF CAGR (5Y) | 83.74% | N/A |
| Total return CAGR (5Y) | 3.38% | N/A |
Frequently asked
- Which has grown faster, PEN or TEM?
- Over the past five years, TEM grew revenue faster — PEN at a 17.52% CAGR versus TEM at 38.24%.
- Is PEN or TEM more profitable?
- PEN runs the higher net margin — PEN at 10.67% versus TEM at -17.77%.
Go deeper
Dig into the metrics
Penumbra P/E ratioPenumbra ROETempus AI ROEPenumbra operating marginTempus AI operating marginPenumbra revenue growthTempus AI revenue growthPenumbra free cash flowTempus AI free cash flow
Penumbra & Tempus AI appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified August 28, 2026.