Pro-Dex, Inc. (PDEX) vs Sionna Therapeutics, Inc. (SION)

A side-by-side comparison of Pro-Dex, Inc. and Sionna Therapeutics, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

Compare
Pro-Dex, Inc. logo
PDEX
Pro-Dex, Inc.
$209M
$65.37HealthcareDelayed quote: Oct 6, 2026, 1:54 PM EDT
Sionna Therapeutics, Inc. logo
SION
Sionna Therapeutics, Inc.
$206M
$4.57HealthcareDelayed quote: Oct 6, 2026, 1:55 PM EDT

Total return — PDEX vs SION

growth of $100 · dividends reinvested · last 2y
PDEX +101.4% (+41.9%/yr)SION -80.6% (-56.0%/yr)PDEX compounded faster over this window
Log scale — wide-divergence pair
101001kStart $1002026$201$19
PDEX SION

PDEX vs SION: by the numbers

  • •PDEX is the larger company ($209M vs $206M market cap).
  • •PDEX is profitable (17.62% net margin) while SION runs a net loss (0.00%).

Metrics side by side

Valuation

MetricPDEXSION
P/E ratio15.87N/A
Forward P/E21.16N/A
PEG ratio0.54N/A
P/S ratio2.69N/A
P/B ratio4.380.78
EV / EBITDA15.20N/A
FCF yield3.30%N/A

Profitability

MetricPDEXSION
Gross margin31.38%0.00%
Operating margin16.75%0.00%
Net margin17.62%0.00%
ROE28.68%-36.64%
ROIC14.99%-40.18%

Growth (annualized)

MetricPDEXSION
Revenue CAGR (5Y)15.32%N/A
EPS CAGR (5Y)29.38%N/A
Total return CAGR (5Y)20.45%N/A

Frequently asked

Is PDEX or SION more profitable?
PDEX runs the higher net margin — PDEX at 17.62% versus SION at 0.00%.

Go deeper

Full PDEX analysisFull SION analysisInteractive comparison tool

Dig into the metrics

Pro-Dex P/E ratioPro-Dex ROESionna Therapeutics ROEPro-Dex operating marginSionna Therapeutics operating marginPro-Dex revenue growthSionna Therapeutics revenue growthPro-Dex free cash flowSionna Therapeutics free cash flow

Pro-Dex & Sionna Therapeutics appear in these rankings

Fastest Revenue Growth StocksHighest ROE StocksHighest 10-Year Total Return Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.