Which has grown faster, PBYI or TKNO?

Over the past five years, TKNO grew revenue faster — PBYI at a 0.29% CAGR versus TKNO at 3.65%.

Is PBYI or TKNO more profitable?

PBYI runs the higher net margin — PBYI at 11.55% versus TKNO at -38.37%.

How have PBYI and TKNO total returns compared?

Over the past 5 years, PBYI delivered 9.26% and TKNO delivered -18.15% annualized total return. Past performance doesn't predict future results.

Puma Biotechnology, Inc. (PBYI) vs Alpha Teknova, Inc. (TKNO)

A side-by-side comparison of Puma Biotechnology, Inc. and Alpha Teknova, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

PBYI

Puma Biotechnology, Inc.

$484M

$9.50HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT

TKNO

Alpha Teknova, Inc.

$469M

$8.75HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT

Total return — PBYI vs TKNO

growth of $100 · dividends reinvested · last 5y

PBYI +0.4% (+0.1%/yr)TKNO -64.0% (-18.5%/yr)PBYI compounded faster over this window

PBYI TKNO

PBYI vs TKNO: by the numbers

•PBYI is the larger company ($484M vs $469M market cap).
•PBYI is profitable (11.55% net margin) while TKNO runs a net loss (-38.37%).
•TKNO grew revenue faster over the past five years (3.65% vs 0.29% CAGR).

Metrics side by side

Valuation

Metric	PBYI	TKNO
P/E ratio	18.40	N/A
Forward P/E	25.00	N/A
P/S ratio	2.09	10.74
P/B ratio	3.49	7.49
EV / EBITDA	10.41	N/A
FCF yield	8.50%	N/A

Profitability

Metric	PBYI	TKNO
Gross margin	74.83%	33.94%
Operating margin	13.16%	-36.19%
Net margin	11.55%	-38.37%
ROE	19.28%	-26.79%
ROIC	18.26%	-17.77%

Growth (annualized)

Metric	PBYI	TKNO
Revenue CAGR (5Y)	0.29%	3.65%
FCF CAGR (5Y)	90.51%	N/A
Total return CAGR (5Y)	9.26%	-18.15%

Frequently asked

Which has grown faster, PBYI or TKNO?: Over the past five years, TKNO grew revenue faster — PBYI at a 0.29% CAGR versus TKNO at 3.65%.
Is PBYI or TKNO more profitable?: PBYI runs the higher net margin — PBYI at 11.55% versus TKNO at -38.37%.
How have PBYI and TKNO total returns compared?: Over the past 5 years, PBYI delivered 9.26% and TKNO delivered -18.15% annualized total return. Past performance doesn't predict future results.

Go deeper

Full PBYI analysis Full TKNO analysis Interactive comparison tool

Dig into the metrics

Puma Biotechnology P/E ratio Puma Biotechnology ROE Alpha Teknova ROE Puma Biotechnology operating margin Alpha Teknova operating margin Puma Biotechnology revenue growth Alpha Teknova revenue growth Puma Biotechnology free cash flow Alpha Teknova free cash flow

Puma Biotechnology & Alpha Teknova appear in these rankings

Highest ROIC Stocks Highest FCF Yield Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.