Which has grown faster, PBYI or SGHT?

Over the past five years, SGHT grew revenue faster — PBYI at a 0.29% CAGR versus SGHT at 16.53%.

Is PBYI or SGHT more profitable?

PBYI runs the higher net margin — PBYI at 11.55% versus SGHT at -35.69%.

How have PBYI and SGHT total returns compared?

Over the past 5 years, PBYI delivered 9.26% and SGHT delivered -18.69% annualized total return. Past performance doesn't predict future results.

Puma Biotechnology, Inc. (PBYI) vs Sight Sciences, Inc. (SGHT)

A side-by-side comparison of Puma Biotechnology, Inc. and Sight Sciences, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

PBYI

Puma Biotechnology, Inc.

$486M

$9.56HealthcareDelayed quote: Oct 6, 2026, 1:00 PM EDT

SGHT

Sight Sciences, Inc.

$468M

$8.61HealthcareDelayed quote: Oct 6, 2026, 12:55 PM EDT

Total return — PBYI vs SGHT

growth of $100 · dividends reinvested · last 5y

PBYI +18.1% (+3.4%/yr)SGHT -73.4% (-23.3%/yr)PBYI compounded faster over this window

PBYI SGHT

PBYI vs SGHT: by the numbers

•PBYI is the larger company ($486M vs $468M market cap).
•PBYI is profitable (11.55% net margin) while SGHT runs a net loss (-35.69%).
•SGHT grew revenue faster over the past five years (16.53% vs 0.29% CAGR).

Metrics side by side

Valuation

Metric	PBYI	SGHT
P/E ratio	18.51	N/A
Forward P/E	25.15	N/A
P/S ratio	2.10	5.62
P/B ratio	3.51	8.86
EV / EBITDA	10.47	N/A
FCF yield	8.45%	N/A

Profitability

Metric	PBYI	SGHT
Gross margin	74.83%	87.96%
Operating margin	13.16%	-47.95%
Net margin	11.55%	-35.69%
ROE	19.28%	-56.26%
ROIC	18.26%	-29.50%

Growth (annualized)

Metric	PBYI	SGHT
Revenue CAGR (5Y)	0.29%	16.53%
FCF CAGR (5Y)	90.51%	N/A
Total return CAGR (5Y)	9.26%	-18.69%

Frequently asked

Which has grown faster, PBYI or SGHT?: Over the past five years, SGHT grew revenue faster — PBYI at a 0.29% CAGR versus SGHT at 16.53%.
Is PBYI or SGHT more profitable?: PBYI runs the higher net margin — PBYI at 11.55% versus SGHT at -35.69%.
How have PBYI and SGHT total returns compared?: Over the past 5 years, PBYI delivered 9.26% and SGHT delivered -18.69% annualized total return. Past performance doesn't predict future results.

Go deeper

Full PBYI analysis Full SGHT analysis Interactive comparison tool

Dig into the metrics

Puma Biotechnology P/E ratio Puma Biotechnology ROE Sight Sciences ROE Puma Biotechnology operating margin Sight Sciences operating margin Puma Biotechnology revenue growth Sight Sciences revenue growth Puma Biotechnology free cash flow Sight Sciences free cash flow

Puma Biotechnology & Sight Sciences appear in these rankings

Fastest Revenue Growth Stocks Highest ROIC Stocks Highest FCF Yield Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.