Palisade Bio, Inc. (PALI) vs Vanda Pharmaceuticals Inc. (VNDA)

A side-by-side comparison of Palisade Bio, Inc. and Vanda Pharmaceuticals Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

Compare

Total return — PALI vs VNDA

growth of $100 · dividends reinvested · last 10y
PALI -100.0% (-71.2%/yr)VNDA -72.8% (-12.2%/yr)VNDA compounded faster over this window
Log scale — wide-divergence pair
00001101001kStart $10020182020202220242026$0$27
PALI VNDA

PALI vs VNDA: by the numbers

  • •VNDA is the larger company ($272M vs $259M market cap).
  • •Both run net losses; VNDA's is the smaller (-127.41% vs -6388.20% net margin).

Metrics side by side

Valuation

MetricPALIVNDA
P/S ratio517.271.26
P/B ratio2.121.23

Profitability

MetricPALIVNDA
Gross margin0.00%92.82%
Operating margin0.00%-69.95%
Net margin-6388.20%-127.41%
ROE-26.24%-124.83%
ROIC-28.96%-74.73%

Growth (annualized)

MetricPALIVNDA
Revenue CAGR (5Y)N/A-3.56%
Total return CAGR (5Y)-76.02%-23.91%

Frequently asked

How have PALI and VNDA total returns compared?
Over the past 10 years, PALI delivered -71.24% and VNDA delivered -11.90% annualized total return. Past performance doesn't predict future results.

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.