Palisade Bio, Inc. (PALI) vs TriSalus Life Sciences, Inc. (TLSI)

A side-by-side comparison of Palisade Bio, Inc. and TriSalus Life Sciences, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

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Total return — PALI vs TLSI

growth of $100 · dividends reinvested · last 6y
PALI -100.0% (-75.4%/yr)TLSI -58.4% (-13.6%/yr)TLSI compounded faster over this window
Log scale — wide-divergence pair
0001101001kStart $10020222023202420252026$0$42
PALI TLSI

PALI vs TLSI: by the numbers

  • •TLSI is the larger company ($263M vs $259M market cap).
  • •Both run net losses; TLSI's is the smaller (-62.59% vs -6388.20% net margin).

Metrics side by side

Valuation

MetricPALITLSI
P/S ratio517.275.83
P/B ratio2.1240.14

Profitability

MetricPALITLSI
Gross margin0.00%85.79%
Operating margin0.00%-59.68%
Net margin-6388.20%-62.59%
ROE-26.24%-430.72%
ROIC-28.96%-59.50%

Growth (annualized)

MetricPALITLSI
Total return CAGR (5Y)-76.02%-15.05%

Frequently asked

How have PALI and TLSI total returns compared?
Over the past 5 years, PALI delivered -76.02% and TLSI delivered -15.05% annualized total return. Past performance doesn't predict future results.

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.