Pacific Biosciences of California, Inc. (PACB) vs SpyGlass Pharma, Inc. Common Stock (SGP)

A side-by-side comparison of Pacific Biosciences of California, Inc. and SpyGlass Pharma, Inc. Common Stock across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

Compare
Pacific Biosciences of California, Inc. logo
PACB
Pacific Biosciences of California, Inc.
$822M
$2.65HealthcareDelayed quote: Oct 6, 2026, 3:55 PM EDT
SpyGlass Pharma, Inc. Common Stock logo
SGP
SpyGlass Pharma, Inc. Common Stock
$840M
$25.13HealthcareDelayed quote: Oct 6, 2026, 3:55 PM EDT

Total return — PACB vs SGP

growth of $100 · dividends reinvested · last 1y
PACB +47.2% (+47.2%/yr)SGP -3.1% (-3.1%/yr)PACB compounded faster over this window
6080100120140Start $100$147$97
PACB SGP

PACB vs SGP: by the numbers

  • •SGP is the larger company ($840M vs $822M market cap).
  • •Both run net losses; SGP's is the smaller (0.00% vs -82.49% net margin).

Metrics side by side

Valuation

MetricPACBSGP
P/S ratio5.16N/A
P/B ratioN/A3.62

Profitability

MetricPACBSGP
Gross margin35.97%0.00%
Operating margin-348.46%0.00%
Net margin-82.49%0.00%
ROEN/A-24.12%
ROIC-23.80%-26.54%

Growth (annualized)

MetricPACBSGP
Revenue CAGR (5Y)8.52%N/A
Total return CAGR (5Y)-35.20%N/A

Go deeper

Full PACB analysisFull SGP analysisInteractive comparison tool

Dig into the metrics

Pacific Biosciences of California ROESpyGlass Pharma, Inc. Common Stock ROEPacific Biosciences of California operating marginSpyGlass Pharma, Inc. Common Stock operating marginPacific Biosciences of California revenue growthSpyGlass Pharma, Inc. Common Stock revenue growthPacific Biosciences of California free cash flowSpyGlass Pharma, Inc. Common Stock free cash flow

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.