Pacific Biosciences of California, Inc. (PACB) vs Rigel Pharmaceuticals, Inc. (RIGL)
A side-by-side comparison of Pacific Biosciences of California, Inc. and Rigel Pharmaceuticals, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.
PACB
Pacific Biosciences of California, Inc.
$2.68HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT
RIGL
Rigel Pharmaceuticals, Inc.
$46.11HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT
Total return — PACB vs RIGL
growth of $100 · dividends reinvested · last 10yPACB -68.1% (-10.8%/yr)RIGL +30.2% (+2.7%/yr)RIGL compounded faster over this window
PACB RIGL
PACB vs RIGL: by the numbers
- •RIGL is the larger company ($853M vs $832M market cap).
- •RIGL is profitable (116.30% net margin) while PACB runs a net loss (-82.49%).
- •RIGL grew revenue faster over the past five years (13.94% vs 8.52% CAGR).
Metrics side by side
Valuation
| Metric | PACB | RIGL |
|---|---|---|
| P/E ratio | N/A | 2.83 |
| Forward P/E | N/A | 13.44 |
| P/S ratio | 5.22 | 3.08 |
| P/B ratio | N/A | 2.01 |
| EV / EBITDA | N/A | 9.28 |
| FCF yield | N/A | 9.31% |
Profitability
| Metric | PACB | RIGL |
|---|---|---|
| Gross margin | 35.97% | 91.39% |
| Operating margin | -348.46% | 42.63% |
| Net margin | -82.49% | 116.30% |
| ROE | N/A | 75.67% |
| ROIC | -23.80% | 18.72% |
Growth (annualized)
| Metric | PACB | RIGL |
|---|---|---|
| Revenue CAGR (5Y) | 8.52% | 13.94% |
| Total return CAGR (5Y) | -35.20% | 6.25% |
Frequently asked
- Which has grown faster, PACB or RIGL?
- Over the past five years, RIGL grew revenue faster — PACB at a 8.52% CAGR versus RIGL at 13.94%.
- Is PACB or RIGL more profitable?
- RIGL runs the higher net margin — PACB at -82.49% versus RIGL at 116.30%.
- How have PACB and RIGL total returns compared?
- Over the past 10 years, PACB delivered -10.80% and RIGL delivered 1.77% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
Rigel Pharmaceuticals P/E ratioPacific Biosciences of California ROERigel Pharmaceuticals ROEPacific Biosciences of California operating marginRigel Pharmaceuticals operating marginPacific Biosciences of California revenue growthRigel Pharmaceuticals revenue growthPacific Biosciences of California free cash flowRigel Pharmaceuticals free cash flow
Pacific Biosciences of California & Rigel Pharmaceuticals appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.