OraSure Technologies, Inc. (OSUR) vs Vanda Pharmaceuticals Inc. (VNDA)

A side-by-side comparison of OraSure Technologies, Inc. and Vanda Pharmaceuticals Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

Compare

Total return — OSUR vs VNDA

growth of $100 · dividends reinvested · last 10y
OSUR -48.7% (-6.5%/yr)VNDA -72.8% (-12.2%/yr)OSUR compounded faster over this window
0100200300Start $10020182020202220242026$51$27
OSUR VNDA

OSUR vs VNDA: by the numbers

  • •VNDA is the larger company ($272M vs $260M market cap).
  • •Both run net losses; OSUR's is the smaller (-43.70% vs -127.41% net margin).
  • •Both shrank revenue over the past five years; VNDA's decline was smaller (-3.56% vs -13.12% CAGR).

Metrics side by side

Valuation

MetricOSURVNDA
P/S ratio2.311.26
P/B ratio0.821.23

Profitability

MetricOSURVNDA
Gross margin41.38%92.82%
Operating margin-59.23%-69.95%
Net margin-43.70%-127.41%
ROE-15.46%-124.83%
ROIC-15.00%-74.73%

Growth (annualized)

MetricOSURVNDA
Revenue CAGR (5Y)-13.12%-3.56%
Total return CAGR (5Y)-17.56%-23.91%

Frequently asked

Which has grown faster, OSUR or VNDA?
Neither grew: over the past five years both shrank revenue, with VNDA's decline the smaller — OSUR at a -13.12% CAGR versus VNDA at -3.56%.
How have OSUR and VNDA total returns compared?
Over the past 10 years, OSUR delivered -6.51% and VNDA delivered -11.90% annualized total return. Past performance doesn't predict future results.

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.