Which has the lower trailing P/E, OSIS or VECO?

OSIS has the lower trailing P/E: OSIS trades at 22.22 and VECO at 154.61. P/E is one valuation measure and does not by itself establish which business is cheaper.

Which has grown faster, OSIS or VECO?

Over the past five years, OSIS grew revenue faster — OSIS at a 9.26% CAGR versus VECO at 5.15%.

Is OSIS or VECO more profitable?

OSIS runs the higher net margin — OSIS at 8.66% versus VECO at 3.40%.

How have OSIS and VECO total returns compared?

Over the past 10 years, OSIS delivered 11.40% and VECO delivered 10.41% annualized total return. Past performance doesn't predict future results.

OSI Systems, Inc. (OSIS) vs Veeco Instruments Inc. (VECO)

A side-by-side comparison of OSI Systems, Inc. and Veeco Instruments Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

OSIS

OSI Systems, Inc.

$3.28B

$198.85TechnologyDelayed quote: Oct 6, 2026, 1:14 PM EDT

VECO

Veeco Instruments Inc.

$3.42B

$56.08TechnologyDelayed quote: Oct 6, 2026, 1:15 PM EDT

Total return — OSIS vs VECO

growth of $100 · dividends reinvested · last 10y

OSIS +194.6% (+11.4%/yr)VECO +190.7% (+11.3%/yr)OSIS compounded faster over this window

OSIS VECO

OSIS vs VECO: by the numbers

•VECO is the larger company ($3.42B vs $3.28B market cap).
•OSIS trades at the lower trailing earnings multiple (22.22 vs 154.61 P/E), one valuation lens rather than an overall verdict.
•OSIS converts more revenue to profit (8.66% vs 3.40% net margin).
•OSIS grew revenue faster over the past five years (9.26% vs 5.15% CAGR).

Metrics side by side

Valuation

Metric	OSIS	VECO
P/E ratio	22.22	154.61
Forward P/E	17.49	N/A
PEG ratio	1.28	N/A
P/S ratio	1.84	5.01
P/B ratio	3.93	3.79
EV / EBITDA	N/A	73.43
FCF yield	N/A	2.49%

Profitability

Metric	OSIS	VECO
Gross margin	33.21%	37.81%
Operating margin	12.26%	3.26%
Net margin	8.66%	3.40%
ROE	18.57%	2.57%
ROIC	8.82%	1.89%

Growth (annualized)

Metric	OSIS	VECO
Revenue CAGR (5Y)	9.26%	5.15%
EPS CAGR (5Y)	16.79%	N/A
FCF CAGR (5Y)	17.50%	21.42%
Total return CAGR (5Y)	15.63%	20.05%

Frequently asked

Which has the lower trailing P/E, OSIS or VECO?: OSIS has the lower trailing P/E: OSIS trades at 22.22 and VECO at 154.61. P/E is one valuation measure and does not by itself establish which business is cheaper.
Which has grown faster, OSIS or VECO?: Over the past five years, OSIS grew revenue faster — OSIS at a 9.26% CAGR versus VECO at 5.15%.
Is OSIS or VECO more profitable?: OSIS runs the higher net margin — OSIS at 8.66% versus VECO at 3.40%.
How have OSIS and VECO total returns compared?: Over the past 10 years, OSIS delivered 11.40% and VECO delivered 10.41% annualized total return. Past performance doesn't predict future results.

Go deeper

Full OSIS analysis Full VECO analysis Interactive comparison tool

Dig into the metrics

OSI Systems P/E ratio Veeco Instruments P/E ratio OSI Systems ROE Veeco Instruments ROE OSI Systems operating margin Veeco Instruments operating margin OSI Systems revenue growth Veeco Instruments revenue growth OSI Systems free cash flow Veeco Instruments free cash flow

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.