Is ORKA or WAY more profitable?

WAY runs the higher net margin — ORKA at 0.00% versus WAY at 11.18%.

Oruka Therapeutics, Inc. (ORKA) vs Waystar Holding Corp. (WAY)

A side-by-side comparison of Oruka Therapeutics, Inc. and Waystar Holding Corp. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

ORKA

Oruka Therapeutics, Inc.

$4.84B

$80.18HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT

WAY

Waystar Holding Corp.

$5.06B

$26.40HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT

Total return — ORKA vs WAY

growth of $100 · dividends reinvested · last 2y

ORKA +237.6% (+83.7%/yr)WAY +27.9% (+13.1%/yr)ORKA compounded faster over this window

ORKA WAY

ORKA vs WAY: by the numbers

•WAY is the larger company ($5.06B vs $4.84B market cap).
•WAY is profitable (11.18% net margin) while ORKA runs a net loss (0.00%).

Metrics side by side

Valuation

Metric	ORKA	WAY
P/E ratio	N/A	37.71
Forward P/E	N/A	15.81
P/S ratio	N/A	4.20
P/B ratio	4.35	1.27
EV / EBITDA	N/A	15.10
FCF yield	N/A	4.86%

Profitability

Metric	ORKA	WAY
Gross margin	0.00%	69.11%
Operating margin	0.00%	22.87%
Net margin	0.00%	11.18%
ROE	-11.92%	3.38%
ROIC	-13.88%	3.38%

Growth (annualized)

Metric	ORKA	WAY
Total return CAGR (5Y)	32.76%	N/A

Frequently asked

Is ORKA or WAY more profitable?: WAY runs the higher net margin — ORKA at 0.00% versus WAY at 11.18%.

Go deeper

Full ORKA analysis Full WAY analysis Interactive comparison tool

Dig into the metrics

Waystar P/E ratio Oruka Therapeutics ROE Waystar ROE Oruka Therapeutics operating margin Waystar operating margin Oruka Therapeutics revenue growth Waystar revenue growth Oruka Therapeutics free cash flow Waystar free cash flow

Oruka Therapeutics & Waystar appear in these rankings

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Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.