Which has grown faster, OPRX or ORGO?

Over the past five years, OPRX grew revenue faster — OPRX at a 13.75% CAGR versus ORGO at 1.05%.

Is OPRX or ORGO more profitable?

OPRX runs the higher net margin — OPRX at 4.66% versus ORGO at -19.76%.

How have OPRX and ORGO total returns compared?

Over the past 5 years, OPRX delivered -36.23% and ORGO delivered -37.41% annualized total return. Past performance doesn't predict future results.

OptimizeRx Corp. (OPRX) vs Organogenesis Holdings Inc. (ORGO)

A side-by-side comparison of OptimizeRx Corp. and Organogenesis Holdings Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

OPRX

OptimizeRx Corp.

$165M

$8.81HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT

ORGO

Organogenesis Holdings Inc.

$172M

$1.34HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT

Total return — OPRX vs ORGO

growth of $100 · dividends reinvested · last 10y

OPRX +258.8% (+13.6%/yr)ORGO -86.8% (-18.3%/yr)OPRX compounded faster over this window

Log scale — wide-divergence pair

OPRX ORGO

OPRX vs ORGO: by the numbers

•ORGO is the larger company ($172M vs $165M market cap).
•OPRX is profitable (4.66% net margin) while ORGO runs a net loss (-19.76%).
•OPRX grew revenue faster over the past five years (13.75% vs 1.05% CAGR).

Metrics side by side

Valuation

Metric	OPRX	ORGO
P/E ratio	37.71	N/A
Forward P/E	9.83	N/A
P/S ratio	1.68	0.38
P/B ratio	1.26	1.16
EV / EBITDA	10.41	216.92
FCF yield	11.10%	12.09%

Profitability

Metric	OPRX	ORGO
Gross margin	63.30%	67.59%
Operating margin	11.45%	9.92%
Net margin	4.66%	-19.76%
ROE	3.51%	-31.32%
ROIC	4.92%	-8.34%

Growth (annualized)

Metric	OPRX	ORGO
Revenue CAGR (5Y)	13.75%	1.05%
FCF CAGR (5Y)	N/A	-5.54%
Total return CAGR (5Y)	-36.23%	-37.41%

Frequently asked

Which has grown faster, OPRX or ORGO?: Over the past five years, OPRX grew revenue faster — OPRX at a 13.75% CAGR versus ORGO at 1.05%.
Is OPRX or ORGO more profitable?: OPRX runs the higher net margin — OPRX at 4.66% versus ORGO at -19.76%.
How have OPRX and ORGO total returns compared?: Over the past 5 years, OPRX delivered -36.23% and ORGO delivered -37.41% annualized total return. Past performance doesn't predict future results.

Go deeper

Full OPRX analysis Full ORGO analysis Interactive comparison tool

Dig into the metrics

OptimizeRx P/E ratio OptimizeRx ROE Organogenesis ROE OptimizeRx operating margin Organogenesis operating margin OptimizeRx revenue growth Organogenesis revenue growth OptimizeRx free cash flow Organogenesis free cash flow

OptimizeRx & Organogenesis appear in these rankings

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Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.