Is OMCL or SEPN more profitable?

OMCL runs the higher net margin — OMCL at 3.13% versus SEPN at -24.51%.

Omnicell, Inc. (OMCL) vs Septerna Inc (SEPN)

A side-by-side comparison of Omnicell, Inc. and Septerna Inc across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

OMCL

Omnicell, Inc.

$1.61B

$35.46HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT

SEPN

Septerna Inc

$1.61B

$35.67HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT

Total return — OMCL vs SEPN

growth of $100 · dividends reinvested · last 2y

OMCL -11.7% (-6.0%/yr)SEPN +77.0% (+33.0%/yr)SEPN compounded faster over this window

OMCL SEPN

OMCL vs SEPN: by the numbers

•OMCL is the larger company ($1.61B vs $1.61B market cap).
•OMCL is profitable (3.13% net margin) while SEPN runs a net loss (-24.51%).

Metrics side by side

Valuation

Metric	OMCL	SEPN
P/E ratio	41.97	N/A
Forward P/E	15.63	N/A
P/S ratio	1.29	16.26
P/B ratio	1.25	4.16
EV / EBITDA	10.75	N/A
FCF yield	8.77%	6.54%

Profitability

Metric	OMCL	SEPN
Gross margin	44.77%	99.57%
Operating margin	4.73%	-175.83%
Net margin	3.13%	-24.51%
ROE	3.03%	-6.27%
ROIC	2.43%	-8.93%

Growth (annualized)

Metric	OMCL	SEPN
Revenue CAGR (5Y)	4.77%	N/A
EPS CAGR (5Y)	-43.29%	N/A
FCF CAGR (5Y)	-8.10%	N/A
Total return CAGR (5Y)	-26.44%	N/A

Frequently asked

Is OMCL or SEPN more profitable?: OMCL runs the higher net margin — OMCL at 3.13% versus SEPN at -24.51%.

Go deeper

Full OMCL analysis Full SEPN analysis Interactive comparison tool

Dig into the metrics

Omnicell P/E ratio Omnicell ROE Septerna ROE Omnicell operating margin Septerna operating margin Omnicell revenue growth Septerna revenue growth Omnicell free cash flow Septerna free cash flow

Omnicell & Septerna appear in these rankings

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Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.