Olema Pharmaceuticals, Inc. (OLMA) vs Wave Life Sciences Ltd. (WVE)

A side-by-side comparison of Olema Pharmaceuticals, Inc. and Wave Life Sciences Ltd. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

Compare

Total return — OLMA vs WVE

growth of $100 · dividends reinvested · last 6y
OLMA -83.2% (-25.7%/yr)WVE -55.9% (-12.7%/yr)WVE compounded faster over this window
050100150200Start $100202120222023202420252026$17$44
OLMA WVE

OLMA vs WVE: by the numbers

  • •WVE is the larger company ($694M vs $692M market cap).
  • •Both run net losses; OLMA's is the smaller (0.00% vs -309.73% net margin).

Metrics side by side

Valuation

MetricOLMAWVE
P/S ratioN/A10.61
P/B ratio1.611.53

Profitability

MetricOLMAWVE
Gross margin0.00%79.28%
Operating margin0.00%-504.09%
Net margin0.00%-309.73%
ROE-47.51%-44.64%
ROIC-50.92%-42.94%

Growth (annualized)

MetricOLMAWVE
Revenue CAGR (5Y)N/A33.08%
Total return CAGR (5Y)-21.50%-4.33%

Frequently asked

How have OLMA and WVE total returns compared?
Over the past 5 years, OLMA delivered -21.50% and WVE delivered -4.33% annualized total return. Past performance doesn't predict future results.

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.