Oculis Holding AG (OCS) vs Puma Biotechnology, Inc. (PBYI)

A side-by-side comparison of Oculis Holding AG and Puma Biotechnology, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

Compare
Oculis Holding AG logo
OCS
Oculis Holding AG
$495M
$8.66HealthcareDelayed quote: Oct 6, 2026, 12:25 PM EDT
Puma Biotechnology, Inc. logo
PBYI
Puma Biotechnology, Inc.
$487M
$9.56HealthcareDelayed quote: Oct 6, 2026, 12:24 PM EDT

Total return — OCS vs PBYI

growth of $100 · dividends reinvested · last 5y
OCS -11.8% (-2.5%/yr)PBYI -5.8% (-1.2%/yr)PBYI compounded faster over this window
0100200300Start $10020222023202420252026$88$94
OCS PBYI

OCS vs PBYI: by the numbers

  • •OCS is the larger company ($495M vs $487M market cap).
  • •PBYI is profitable (11.55% net margin) while OCS runs a net loss (-32724.20%).

Metrics side by side

Valuation

MetricOCSPBYI
P/E ratioN/A18.52
Forward P/EN/A25.16
P/S ratio1622.782.10
P/B ratio1.823.51
EV / EBITDAN/A10.48
FCF yieldN/A8.44%

Profitability

MetricOCSPBYI
Gross margin0.00%74.83%
Operating margin0.00%13.16%
Net margin-32724.20%11.55%
ROE-36.79%19.28%
ROIC-39.63%18.26%

Growth (annualized)

MetricOCSPBYI
Revenue CAGR (5Y)N/A0.29%
FCF CAGR (5Y)N/A90.51%
Total return CAGR (5Y)-2.41%9.26%

Frequently asked

Is OCS or PBYI more profitable?
PBYI runs the higher net margin — OCS at -32724.20% versus PBYI at 11.55%.
How have OCS and PBYI total returns compared?
Over the past 5 years, OCS delivered -2.41% and PBYI delivered 9.26% annualized total return. Past performance doesn't predict future results.

Go deeper

Full OCS analysisFull PBYI analysisInteractive comparison tool

Dig into the metrics

Puma Biotechnology P/E ratioOculis Holding AG ROEPuma Biotechnology ROEOculis Holding AG operating marginPuma Biotechnology operating marginOculis Holding AG revenue growthPuma Biotechnology revenue growthOculis Holding AG free cash flowPuma Biotechnology free cash flow

Oculis Holding AG & Puma Biotechnology appear in these rankings

Highest ROIC StocksHighest FCF Yield Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.