How have NXTC and TXMD total returns compared?

Over the past 5 years, NXTC delivered -44.29% and TXMD delivered -44.16% annualized total return. Past performance doesn't predict future results.

NextCure, Inc. (NXTC) vs TherapeuticsMD, Inc. (TXMD)

A side-by-side comparison of NextCure, Inc. and TherapeuticsMD, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

NXTC

NextCure, Inc.

$21M

$5.69HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT

TXMD

TherapeuticsMD, Inc.

$23M

$2.02HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT

Total return — NXTC vs TXMD

growth of $100 · dividends reinvested · last 7y

NXTC -97.9% (-42.4%/yr)TXMD -98.9% (-47.6%/yr)NXTC compounded faster over this window

NXTC TXMD

NXTC vs TXMD: by the numbers

•TXMD is the larger company ($23M vs $21M market cap).
•Both run net losses; NXTC's is the smaller (0.00% vs -6.64% net margin).

Metrics side by side

Valuation

Metric	NXTC	TXMD
Forward P/E	N/A	11.88
P/S ratio	N/A	7.15
P/B ratio	1.69	0.86
FCF yield	N/A	13.34%

Profitability

Metric	NXTC	TXMD
Gross margin	0.00%	100.00%
Operating margin	0.00%	-139.44%
Net margin	0.00%	-6.64%
ROE	-351.86%	-0.80%
ROIC	-259.91%	-11.84%

Growth (annualized)

Metric	NXTC	TXMD
Revenue CAGR (5Y)	N/A	-47.86%
Total return CAGR (5Y)	-44.29%	-44.16%

Frequently asked

How have NXTC and TXMD total returns compared?: Over the past 5 years, NXTC delivered -44.29% and TXMD delivered -44.16% annualized total return. Past performance doesn't predict future results.

Go deeper

Full NXTC analysis Full TXMD analysis Interactive comparison tool

Dig into the metrics

NextCure ROE TherapeuticsMD ROE NextCure operating margin TherapeuticsMD operating margin NextCure revenue growth TherapeuticsMD revenue growth NextCure free cash flow TherapeuticsMD free cash flow

NextCure & TherapeuticsMD appear in these rankings

Highest FCF Yield Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.