Novo Nordisk A/S (NVO) vs Pfizer Inc. (PFE)

A side-by-side comparison of Novo Nordisk A/S and Pfizer Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of September 13, 2026. Differences are shown without an overall score or investment verdict.

Compare

Total returnNVO vs PFE

growth of $100 · dividends reinvested · last 10y
NVO +135.8% (+9.0%/yr)PFE +37.0% (+3.2%/yr)NVO compounded faster over this window
200400600Start $10020182020202220242026$236$137
NVO PFE

NVO vs PFE: by the numbers

  • NVO is the larger company ($188.86B vs $157.02B market cap).
  • NVO trades at the lower trailing earnings multiple (10.48 vs 36.40 P/E), one valuation lens rather than an overall verdict.
  • NVO converts more revenue to profit (35.33% vs 6.81% net margin).
  • NVO grew revenue faster over the past five years (19.76% vs 6.29% CAGR).
  • PFE pays the higher dividend yield (6.20% vs 4.17%).

Metrics side by side

Valuation

MetricNVOPFE
P/E ratio10.4836.40
Forward P/EN/A9.26
P/S ratio3.702.47
P/B ratio5.601.84
EV / EBITDA7.7610.11
FCF yield3.94%7.00%

Profitability

MetricNVOPFE
Gross margin80.64%71.32%
Operating margin43.10%25.08%
Net margin35.33%6.81%
ROE53.50%5.09%
ROIC30.21%9.33%

Dividends

MetricNVOPFE
Dividend yield4.17%6.20%
Payout ratio44.27%227.27%

Growth (annualized)

MetricNVOPFE
Revenue CAGR (5Y)19.76%6.29%
EPS CAGR (5Y)19.59%-3.78%
FCF CAGR (5Y)-1.45%-3.11%
Total return CAGR (5Y)-0.65%-4.53%

Frequently asked

Which has the lower trailing P/E, NVO or PFE?
NVO has the lower trailing P/E: NVO trades at 10.48 and PFE at 36.40. P/E is one valuation measure and does not by itself establish which business is cheaper.
Which has grown faster, NVO or PFE?
Over the past five years, NVO grew revenue faster — NVO at a 19.76% CAGR versus PFE at 6.29%.
Does NVO or PFE pay a bigger dividend?
NVO yields 4.17% and PFE yields 6.20% based on trailing dividends and the latest price.
Is NVO or PFE more profitable?
NVO runs the higher net margin — NVO at 35.33% versus PFE at 6.81%.
How have NVO and PFE total returns compared?
Over the past 10 years, NVO delivered 9.46% and PFE delivered 3.15% annualized total return. Past performance doesn't predict future results.

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified September 13, 2026.