Novo Nordisk A/S (NVO) vs Pfizer Inc. (PFE)
A side-by-side comparison of Novo Nordisk A/S and Pfizer Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of September 13, 2026. Differences are shown without an overall score or investment verdict.
NVO
Novo Nordisk A/S
$42.53HealthcareDelayed quote: Sep 15, 2026, 4:00 PM EDT
PFE
Pfizer Inc.
$27.55HealthcareDelayed quote: Sep 15, 2026, 4:02 PM EDT
Total return — NVO vs PFE
growth of $100 · dividends reinvested · last 10yNVO +135.8% (+9.0%/yr)PFE +37.0% (+3.2%/yr)NVO compounded faster over this window
NVO PFE
NVO vs PFE: by the numbers
- •NVO is the larger company ($188.86B vs $157.02B market cap).
- •NVO trades at the lower trailing earnings multiple (10.48 vs 36.40 P/E), one valuation lens rather than an overall verdict.
- •NVO converts more revenue to profit (35.33% vs 6.81% net margin).
- •NVO grew revenue faster over the past five years (19.76% vs 6.29% CAGR).
- •PFE pays the higher dividend yield (6.20% vs 4.17%).
Metrics side by side
Valuation
| Metric | NVO | PFE |
|---|---|---|
| P/E ratio | 10.48 | 36.40 |
| Forward P/E | N/A | 9.26 |
| P/S ratio | 3.70 | 2.47 |
| P/B ratio | 5.60 | 1.84 |
| EV / EBITDA | 7.76 | 10.11 |
| FCF yield | 3.94% | 7.00% |
Profitability
| Metric | NVO | PFE |
|---|---|---|
| Gross margin | 80.64% | 71.32% |
| Operating margin | 43.10% | 25.08% |
| Net margin | 35.33% | 6.81% |
| ROE | 53.50% | 5.09% |
| ROIC | 30.21% | 9.33% |
Dividends
| Metric | NVO | PFE |
|---|---|---|
| Dividend yield | 4.17% | 6.20% |
| Payout ratio | 44.27% | 227.27% |
Growth (annualized)
| Metric | NVO | PFE |
|---|---|---|
| Revenue CAGR (5Y) | 19.76% | 6.29% |
| EPS CAGR (5Y) | 19.59% | -3.78% |
| FCF CAGR (5Y) | -1.45% | -3.11% |
| Total return CAGR (5Y) | -0.65% | -4.53% |
Frequently asked
- Which has the lower trailing P/E, NVO or PFE?
- NVO has the lower trailing P/E: NVO trades at 10.48 and PFE at 36.40. P/E is one valuation measure and does not by itself establish which business is cheaper.
- Which has grown faster, NVO or PFE?
- Over the past five years, NVO grew revenue faster — NVO at a 19.76% CAGR versus PFE at 6.29%.
- Does NVO or PFE pay a bigger dividend?
- NVO yields 4.17% and PFE yields 6.20% based on trailing dividends and the latest price.
- Is NVO or PFE more profitable?
- NVO runs the higher net margin — NVO at 35.33% versus PFE at 6.81%.
- How have NVO and PFE total returns compared?
- Over the past 10 years, NVO delivered 9.46% and PFE delivered 3.15% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
Novo Nordisk A/S P/E ratioPfizer P/E ratioNovo Nordisk A/S dividend yieldPfizer dividend yieldNovo Nordisk A/S ROEPfizer ROENovo Nordisk A/S operating marginPfizer operating marginNovo Nordisk A/S revenue growthPfizer revenue growthNovo Nordisk A/S free cash flowPfizer free cash flow
Novo Nordisk A/S & Pfizer appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified September 13, 2026.