Novavax, Inc. (NVAX) vs Sarepta Therapeutics, Inc. (SRPT)

A side-by-side comparison of Novavax, Inc. and Sarepta Therapeutics, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

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Total return — NVAX vs SRPT

growth of $100 · dividends reinvested · last 10y
NVAX -68.6% (-10.9%/yr)SRPT -67.4% (-10.6%/yr)SRPT compounded faster over this window
0200400600800Start $10020182020202220242026$31$33
NVAX SRPT

NVAX vs SRPT: by the numbers

  • •NVAX is the larger company ($1.82B vs $1.81B market cap).
  • •Both run net losses; SRPT's is the smaller (-6.93% vs -59.87% net margin).
  • •NVAX grew revenue faster over the past five years (118.86% vs 26.90% CAGR).

Metrics side by side

Valuation

MetricNVAXSRPT
Forward P/EN/A5.34
P/S ratio4.410.92
P/B ratioN/A1.19

Profitability

MetricNVAXSRPT
Gross margin93.67%58.56%
Operating margin50.14%-29.92%
Net margin-59.87%-6.93%
ROEN/A-8.95%
ROIC-36.37%-5.33%

Growth (annualized)

MetricNVAXSRPT
Revenue CAGR (5Y)118.86%26.90%
Total return CAGR (5Y)-40.61%-28.74%

Frequently asked

Which has grown faster, NVAX or SRPT?
Over the past five years, NVAX grew revenue faster — NVAX at a 118.86% CAGR versus SRPT at 26.90%.
How have NVAX and SRPT total returns compared?
Over the past 10 years, NVAX delivered -10.98% and SRPT delivered -11.94% annualized total return. Past performance doesn't predict future results.

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.