Intellia Therapeutics, Inc. (NTLA) vs TransMedics Group, Inc. (TMDX)

A side-by-side comparison of Intellia Therapeutics, Inc. and TransMedics Group, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 2, 2026. Differences are shown without an overall score or investment verdict.

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Total return — NTLA vs TMDX

growth of $100 · dividends reinvested · last 7y
NTLA -16.2% (-2.5%/yr)TMDX +251.7% (+19.7%/yr)TMDX compounded faster over this window
05001kStart $100202120232025$84$352
NTLA TMDX

NTLA vs TMDX: by the numbers

  • •TMDX is the larger company ($2.74B vs $1.72B market cap).
  • •TMDX is profitable (22.69% net margin) while NTLA runs a net loss (-672.16%).
  • •TMDX grew revenue faster over the past five years (86.12% vs 7.31% CAGR).

Metrics side by side

Valuation

MetricNTLATMDX
P/E ratioN/A20.55
Forward P/EN/A54.08
P/S ratio28.854.10
P/B ratio2.365.29
EV / EBITDAN/A26.57
FCF yieldN/A2.88%

Profitability

MetricNTLATMDX
Gross margin76.47%58.69%
Operating margin-651.67%12.21%
Net margin-672.16%22.69%
ROE-54.96%29.28%
ROIC-54.45%5.87%

Growth (annualized)

MetricNTLATMDX
Revenue CAGR (5Y)7.31%86.12%
Total return CAGR (5Y)-38.17%19.20%

Frequently asked

Which has grown faster, NTLA or TMDX?
Over the past five years, TMDX grew revenue faster — NTLA at a 7.31% CAGR versus TMDX at 86.12%.
Is NTLA or TMDX more profitable?
TMDX runs the higher net margin — NTLA at -672.16% versus TMDX at 22.69%.
How have NTLA and TMDX total returns compared?
Over the past 5 years, NTLA delivered -38.17% and TMDX delivered 19.20% annualized total return. Past performance doesn't predict future results.

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 2, 2026.