Nkarta, Inc. (NKTX) vs OptimizeRx Corp. (OPRX)
A side-by-side comparison of Nkarta, Inc. and OptimizeRx Corp. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.
NKTX
Nkarta, Inc.
$2.34HealthcareDelayed quote: Oct 6, 2026, 3:05 PM EDT
OPRX
OptimizeRx Corp.
$8.83HealthcareDelayed quote: Oct 6, 2026, 3:05 PM EDT
Total return — NKTX vs OPRX
growth of $100 · dividends reinvested · last 6yNKTX -94.7% (-38.7%/yr)OPRX -39.4% (-8.0%/yr)OPRX compounded faster over this window
Log scale — wide-divergence pair
NKTX OPRX
NKTX vs OPRX: by the numbers
- •NKTX is the larger company ($168M vs $166M market cap).
- •OPRX is profitable (4.66% net margin) while NKTX runs a net loss (0.00%).
Metrics side by side
Valuation
| Metric | NKTX | OPRX |
|---|---|---|
| P/E ratio | N/A | 37.80 |
| Forward P/E | N/A | 9.85 |
| P/S ratio | N/A | 1.68 |
| P/B ratio | 0.68 | 1.26 |
| EV / EBITDA | N/A | 10.43 |
| FCF yield | N/A | 11.08% |
Profitability
| Metric | NKTX | OPRX |
|---|---|---|
| Gross margin | 0.00% | 63.30% |
| Operating margin | 0.00% | 11.45% |
| Net margin | 0.00% | 4.66% |
| ROE | -47.36% | 3.51% |
| ROIC | -42.11% | 4.92% |
Growth (annualized)
| Metric | NKTX | OPRX |
|---|---|---|
| Revenue CAGR (5Y) | N/A | 13.75% |
| Total return CAGR (5Y) | -37.28% | -36.23% |
Frequently asked
- Is NKTX or OPRX more profitable?
- OPRX runs the higher net margin — NKTX at 0.00% versus OPRX at 4.66%.
- How have NKTX and OPRX total returns compared?
- Over the past 5 years, NKTX delivered -37.28% and OPRX delivered -36.23% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
OptimizeRx P/E ratioNkarta ROEOptimizeRx ROENkarta operating marginOptimizeRx operating marginNkarta revenue growthOptimizeRx revenue growthNkarta free cash flowOptimizeRx free cash flow
Nkarta & OptimizeRx appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.