Nektar Therapeutics (NKTR) vs Tyra Biosciences, Inc. (TYRA)
A side-by-side comparison of Nektar Therapeutics and Tyra Biosciences, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.
NKTR
Nektar Therapeutics
$39.74HealthcareDelayed quote: Oct 6, 2026, 3:05 PM EDT
TYRA
Tyra Biosciences, Inc.
$20.18HealthcareDelayed quote: Oct 6, 2026, 3:05 PM EDT
Total return — NKTR vs TYRA
growth of $100 · dividends reinvested · last 5yNKTR -82.6% (-29.5%/yr)TYRA -19.5% (-4.2%/yr)TYRA compounded faster over this window
NKTR TYRA
NKTR vs TYRA: by the numbers
- •TYRA is the larger company ($1.20B vs $1.14B market cap).
- •Both run net losses; TYRA's is the smaller (0.00% vs -287.84% net margin).
Metrics side by side
Valuation
| Metric | NKTR | TYRA |
|---|---|---|
| P/S ratio | 20.88 | N/A |
| P/B ratio | 1.26 | 3.40 |
Profitability
| Metric | NKTR | TYRA |
|---|---|---|
| Gross margin | 99.36% | 0.00% |
| Operating margin | -240.38% | 0.00% |
| Net margin | -287.84% | 0.00% |
| ROE | -17.40% | -42.01% |
| ROIC | -12.53% | -44.73% |
Growth (annualized)
| Metric | NKTR | TYRA |
|---|---|---|
| Revenue CAGR (5Y) | -12.34% | N/A |
| Total return CAGR (5Y) | -30.33% | 9.23% |
Frequently asked
- How have NKTR and TYRA total returns compared?
- Over the past 5 years, NKTR delivered -30.33% and TYRA delivered 9.23% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.