Which has grown faster, NEPH or SCLX?

Over the past five years, NEPH grew revenue faster — NEPH at a 16.99% CAGR versus SCLX at 3.58%.

Is NEPH or SCLX more profitable?

NEPH runs the higher net margin — NEPH at 8.38% versus SCLX at -1414.57%.

How have NEPH and SCLX total returns compared?

Over the past 5 years, NEPH delivered -15.93% and SCLX delivered -59.50% annualized total return. Past performance doesn't predict future results.

Nephros, Inc. (NEPH) vs Scilex Holding Company (SCLX)

A side-by-side comparison of Nephros, Inc. and Scilex Holding Company across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

NEPH

Nephros, Inc.

$33M

$3.02HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT

SCLX

Scilex Holding Company

$34M

$3.96HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT

Total return — NEPH vs SCLX

growth of $100 · dividends reinvested · last 6y

NEPH -57.6% (-13.3%/yr)SCLX -98.9% (-52.8%/yr)NEPH compounded faster over this window

Log scale — wide-divergence pair

NEPH SCLX

NEPH vs SCLX: by the numbers

•SCLX is the larger company ($34M vs $33M market cap).
•NEPH is profitable (8.38% net margin) while SCLX runs a net loss (-1414.57%).
•NEPH grew revenue faster over the past five years (16.99% vs 3.58% CAGR).

Metrics side by side

Valuation

Metric	NEPH	SCLX
P/E ratio	19.03	N/A
Forward P/E	19.28	N/A
P/S ratio	1.58	1.06
P/B ratio	2.74	N/A
EV / EBITDA	16.41	N/A

Profitability

Metric	NEPH	SCLX
Gross margin	60.31%	49.68%
Operating margin	7.92%	-903.52%
Net margin	8.38%	-1414.57%
ROE	14.51%	N/A
ROIC	12.67%	N/A

Growth (annualized)

Metric	NEPH	SCLX
Revenue CAGR (5Y)	16.99%	3.58%
Total return CAGR (5Y)	-15.93%	-59.50%

Frequently asked

Which has grown faster, NEPH or SCLX?: Over the past five years, NEPH grew revenue faster — NEPH at a 16.99% CAGR versus SCLX at 3.58%.
Is NEPH or SCLX more profitable?: NEPH runs the higher net margin — NEPH at 8.38% versus SCLX at -1414.57%.
How have NEPH and SCLX total returns compared?: Over the past 5 years, NEPH delivered -15.93% and SCLX delivered -59.50% annualized total return. Past performance doesn't predict future results.

Go deeper

Full NEPH analysis Full SCLX analysis Interactive comparison tool

Dig into the metrics

Nephros P/E ratio Nephros ROE Scilex ROE Nephros operating margin Scilex operating margin Nephros revenue growth Scilex revenue growth Nephros free cash flow Scilex free cash flow

Nephros & Scilex appear in these rankings

Fastest Revenue Growth Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.