Nautilus Biotechnolgy, Inc. (NAUT) vs Quantum-Si incorporated (QSI)

A side-by-side comparison of Nautilus Biotechnolgy, Inc. and Quantum-Si incorporated across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

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Total return — NAUT vs QSI

growth of $100 · dividends reinvested · last 6y
NAUT -82.0% (-24.9%/yr)QSI -87.0% (-28.9%/yr)NAUT compounded faster over this window
050100150200Start $100202120222023202420252026$18$13
NAUT QSI

NAUT vs QSI: by the numbers

  • •QSI is the larger company ($248M vs $233M market cap).
  • •Both run net losses; QSI's is the smaller (-6138.26% vs -29747.89% net margin).

Metrics side by side

Valuation

MetricNAUTQSI
P/S ratio1225.67154.68
P/B ratio1.781.38

Profitability

MetricNAUTQSI
Gross margin0.00%47.33%
Operating margin0.00%-3996.72%
Net margin-29747.89%-6138.26%
ROE-43.11%-54.67%
ROIC-40.52%-51.87%

Growth (annualized)

MetricNAUTQSI
Total return CAGR (5Y)-20.56%-31.06%

Frequently asked

How have NAUT and QSI total returns compared?
Over the past 5 years, NAUT delivered -20.56% and QSI delivered -31.06% annualized total return. Past performance doesn't predict future results.

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.