Niagen Bioscience Inc (NAGE) vs Profound Medical Corp. (PROF)
A side-by-side comparison of Niagen Bioscience Inc and Profound Medical Corp. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.
NAGE
Niagen Bioscience Inc
$2.70HealthcareDelayed quote: Oct 6, 2026, 1:49 PM EDT
PROF
Profound Medical Corp.
$6.13HealthcareDelayed quote: Oct 6, 2026, 1:49 PM EDT
Total return — NAGE vs PROF
growth of $100 · dividends reinvested · last 7yNAGE -10.4% (-1.6%/yr)PROF -37.9% (-6.6%/yr)NAGE compounded faster over this window
NAGE PROF
NAGE vs PROF: by the numbers
- •PROF is the larger company ($223M vs $215M market cap).
- •NAGE is profitable (12.39% net margin) while PROF runs a net loss (-171.72%).
- •PROF grew revenue faster over the past five years (16.55% vs 15.80% CAGR).
Metrics side by side
Valuation
| Metric | NAGE | PROF |
|---|---|---|
| P/E ratio | 14.46 | N/A |
| Forward P/E | 18.69 | N/A |
| P/S ratio | 1.66 | 11.72 |
| P/B ratio | 2.60 | 4.47 |
| EV / EBITDA | 14.40 | N/A |
| FCF yield | 2.64% | N/A |
Profitability
| Metric | NAGE | PROF |
|---|---|---|
| Gross margin | 64.24% | 71.79% |
| Operating margin | 6.67% | -256.27% |
| Net margin | 12.39% | -171.72% |
| ROE | 19.38% | -65.59% |
| ROIC | 8.84% | -61.03% |
Growth (annualized)
| Metric | NAGE | PROF |
|---|---|---|
| Revenue CAGR (5Y) | 15.80% | 16.55% |
| Total return CAGR (5Y) | -15.72% | -15.23% |
Frequently asked
- Which has grown faster, NAGE or PROF?
- Over the past five years, PROF grew revenue faster — NAGE at a 15.80% CAGR versus PROF at 16.55%.
- Is NAGE or PROF more profitable?
- NAGE runs the higher net margin — NAGE at 12.39% versus PROF at -171.72%.
- How have NAGE and PROF total returns compared?
- Over the past 5 years, NAGE delivered -15.72% and PROF delivered -15.23% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
Niagen Bioscience P/E ratioNiagen Bioscience ROEProfound Medical ROENiagen Bioscience operating marginProfound Medical operating marginNiagen Bioscience revenue growthProfound Medical revenue growthNiagen Bioscience free cash flowProfound Medical free cash flow
Niagen Bioscience & Profound Medical appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.