Merck & Co., Inc. (MRK) vs Pfizer Inc. (PFE)
MRK leads on 9 of 16 compared metrics, though PFE is the cheaper stock.
A side-by-side comparison of Merck & Co., Inc. and Pfizer Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of June 13, 2026. The ● marks the stronger figure on each row (cheaper multiple, higher margin/return).
Total return — MRK vs PFE
growth of $100 · last 30yMRK +287.9%PFE +128.5%MRK compounded faster
MRK PFE
MRK vs PFE: by the numbers
- •MRK is the larger company ($294.03B vs $149.38B market cap).
- •PFE trades at the lower earnings multiple (20.01 vs 33.54 P/E).
- •MRK converts more revenue to profit (13.62% vs 11.83% net margin).
- •MRK grew revenue faster over the past five years (8.60% vs 8.22% CAGR).
- •PFE pays the higher dividend yield (6.56% vs 2.79%).
Which is better, MRK or PFE?
Metric tally: MRK 9 · PFE 7It depends on what you're optimizing for:
ValuePFE(lower P/E)
GrowthMRK(faster 5Y revenue CAGR)
IncomePFE(higher dividend yield)
QualityMRK(higher ROIC)
Valuation
| Metric | MRK | PFE |
|---|---|---|
| P/E ratio | 33.54 | 20.01● |
| Forward P/E | 12.35 | 9.25● |
| P/S ratio | 4.49 | 2.37● |
| P/B ratio | 6.41 | 1.67● |
| PEG ratio | 1.81 | — |
| EV / EBITDA | 19.58 | 12.72● |
| FCF yield | 4.80% | 6.31%● |
Profitability
| Metric | MRK | PFE |
|---|---|---|
| Gross margin | 75.91%● | 69.35% |
| Operating margin | 27.59%● | 23.45% |
| Net margin | 13.62%● | 11.83% |
| ROE | 19.48%● | 8.31% |
| ROIC | 18.27%● | 8.84% |
Dividends
| Metric | MRK | PFE |
|---|---|---|
| Dividend yield | 2.79% | 6.56%● |
| Payout ratio | 45.48% | 126.47% |
Growth (annualized)
| Metric | MRK | PFE |
|---|---|---|
| Revenue CAGR (5Y) | 8.60%● | 8.22% |
| EPS CAGR (5Y) | 21.21%● | -3.78% |
| FCF CAGR (5Y) | 15.69%● | -3.79% |
| Total return CAGR (5Y) | 12.79%● | -3.33% |
Frequently asked
- Which is better, MRK or PFE?
- It depends on your goal. value: PFE (lower P/E); growth: MRK (faster 5Y revenue CAGR); income: PFE (higher dividend yield); quality: MRK (higher ROIC). Across all compared metrics, MRK leads 9 to 7.
- Is MRK or PFE cheaper?
- On trailing earnings, PFE is cheaper: MRK trades at a 33.54 P/E and PFE at 20.01.
- Which has grown faster, MRK or PFE?
- Over the past five years, MRK grew revenue faster — MRK at a 8.60% CAGR versus PFE at 8.22%.
- Does MRK or PFE pay a bigger dividend?
- MRK yields 2.79% and PFE yields 6.56% based on trailing dividends and the latest price.
- Is MRK or PFE more profitable?
- MRK runs the higher net margin — MRK at 13.62% versus PFE at 11.83%.
- Which has been the better investment, MRK or PFE?
- Over the past 10-year, MRK delivered the higher annualized total return — MRK at 11.57% versus PFE at 2.13%. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
Merck & P/E ratioPfizer P/E ratioMerck & dividend yieldPfizer dividend yieldMerck & ROEPfizer ROEMerck & operating marginPfizer operating marginMerck & revenue growthPfizer revenue growthMerck & free cash flowPfizer free cash flow
Merck & & Pfizer appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified June 13, 2026.