Merck & Co., Inc. (MRK) vs Novo Nordisk A/S (NVO)

A side-by-side comparison of Merck & Co., Inc. and Novo Nordisk A/S across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of September 13, 2026. Differences are shown without an overall score or investment verdict.

Compare

Total returnMRK vs NVO

growth of $100 · dividends reinvested · last 10y
MRK +226.9% (+12.6%/yr)NVO +135.8% (+9.0%/yr)MRK compounded faster over this window
200400600Start $10020182020202220242026$327$236
MRK NVO

MRK vs NVO: by the numbers

  • MRK is the larger company ($354.52B vs $189.15B market cap).
  • NVO trades at the lower trailing earnings multiple (10.50 vs 114.83 P/E), one valuation lens rather than an overall verdict.
  • NVO converts more revenue to profit (35.33% vs 4.78% net margin).
  • NVO grew revenue faster over the past five years (19.76% vs 7.87% CAGR).
  • NVO pays the higher dividend yield (4.17% vs 2.33%).

Metrics side by side

Valuation

MetricMRKNVO
P/E ratio114.8310.50
Forward P/E52.27N/A
P/S ratio5.343.70
P/B ratio8.455.61
EV / EBITDA22.707.77
FCF yield4.53%3.94%

Profitability

MetricMRKNVO
Gross margin75.38%80.64%
Operating margin36.17%43.10%
Net margin4.78%35.33%
ROE7.57%53.50%
ROIC5.80%30.21%

Dividends

MetricMRKNVO
Dividend yield2.33%4.17%
Payout ratio268.80%44.27%

Growth (annualized)

MetricMRKNVO
Revenue CAGR (5Y)7.87%19.76%
EPS CAGR (5Y)21.21%19.59%
FCF CAGR (5Y)23.61%-1.45%
Total return CAGR (5Y)18.01%-0.65%

Frequently asked

Which has the lower trailing P/E, MRK or NVO?
NVO has the lower trailing P/E: MRK trades at 114.83 and NVO at 10.50. P/E is one valuation measure and does not by itself establish which business is cheaper.
Which has grown faster, MRK or NVO?
Over the past five years, NVO grew revenue faster — MRK at a 7.87% CAGR versus NVO at 19.76%.
Does MRK or NVO pay a bigger dividend?
MRK yields 2.33% and NVO yields 4.17% based on trailing dividends and the latest price.
Is MRK or NVO more profitable?
NVO runs the higher net margin — MRK at 4.78% versus NVO at 35.33%.
How have MRK and NVO total returns compared?
Over the past 10 years, MRK delivered 12.62% and NVO delivered 9.46% annualized total return. Past performance doesn't predict future results.

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified September 13, 2026.