MapLight Therapeutics, Inc. (MPLT) vs Shoulder Innovations, Inc. (SI)
A side-by-side comparison of MapLight Therapeutics, Inc. and Shoulder Innovations, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.
MPLT
MapLight Therapeutics, Inc.
$9.69HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT
SI
Shoulder Innovations, Inc.
$19.14HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT
Total return — MPLT vs SI
growth of $100 · dividends reinvested · last 1yMPLT -49.4% (-49.4%/yr)SI +59.2% (+59.2%/yr)SI compounded faster over this window
MPLT SI
MPLT vs SI: by the numbers
- •MPLT is the larger company ($411M vs $397M market cap).
- •Both run net losses; MPLT's is the smaller (0.00% vs -58.33% net margin).
Metrics side by side
Valuation
| Metric | MPLT | SI |
|---|---|---|
| P/S ratio | N/A | 6.61 |
| P/B ratio | 1.18 | 3.19 |
Profitability
| Metric | MPLT | SI |
|---|---|---|
| Gross margin | 0.00% | 77.34% |
| Operating margin | 0.00% | -58.53% |
| Net margin | 0.00% | -58.33% |
| ROE | -65.99% | -28.18% |
| ROIC | -69.35% | -25.26% |
Go deeper
Dig into the metrics
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.