MeiraGTx Holdings plc (MGTX) vs Seaport Therapeutics, Inc. Common Stock (SPTX)

A side-by-side comparison of MeiraGTx Holdings plc and Seaport Therapeutics, Inc. Common Stock across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

Compare
MeiraGTx Holdings plc logo
MGTX
MeiraGTx Holdings plc
$982M
$10.60HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT
Seaport Therapeutics, Inc. Common Stock logo
SPTX
Seaport Therapeutics, Inc. Common Stock
$930M
$17.37HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT

Total return — MGTX vs SPTX

growth of $100 · dividends reinvested · last 1y
MGTX +18.4% (+18.4%/yr)SPTX -6.8% (-6.8%/yr)MGTX compounded faster over this window
80100120140160Start $100$118$93
MGTX SPTX

MGTX vs SPTX: by the numbers

  • •MGTX is the larger company ($982M vs $930M market cap).
  • •MGTX is profitable (19.87% net margin) while SPTX runs a net loss (0.00%).

Metrics side by side

Valuation

MetricMGTXSPTX
P/E ratio14.93N/A
Forward P/E35.33N/A
P/S ratio2.47N/A
P/B ratio4.552.20
EV / EBITDA4.84N/A

Profitability

MetricMGTXSPTX
Gross margin97.19%0.00%
Operating margin-130.20%0.00%
Net margin19.87%0.00%
ROE36.64%N/A
ROIC52.81%-36.95%

Growth (annualized)

MetricMGTXSPTX
Revenue CAGR (5Y)84.52%N/A
Total return CAGR (5Y)-3.10%N/A

Some values include inputs from SEC filing.

Frequently asked

Is MGTX or SPTX more profitable?
MGTX runs the higher net margin — MGTX at 19.87% versus SPTX at 0.00%.

Go deeper

Full MGTX analysisFull SPTX analysisInteractive comparison tool

Dig into the metrics

MeiraGTx P/E ratioMeiraGTx ROESeaport Therapeutics, Inc. Common Stock ROEMeiraGTx operating marginSeaport Therapeutics, Inc. Common Stock operating marginMeiraGTx revenue growthSeaport Therapeutics, Inc. Common Stock revenue growthMeiraGTx free cash flowSeaport Therapeutics, Inc. Common Stock free cash flow

MeiraGTx & Seaport Therapeutics, Inc. Common Stock appear in these rankings

Fastest Revenue Growth StocksHighest ROE StocksHighest ROIC StocksLowest P/E Ratio Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.